Comprehensive Guide to 2,5-Dibromo-3-Fluoropyridine
Table of Contents
- Product Overview & Key Specifications
- Applications of 2,5-Dibromo-3-Fluoropyridine
- Usage Scenarios & Case Studies
- Client Success Stories
- Request a Quote
1. Product Overview & Key Specifications
2,5-Dibromo-3-Fluoropyridine (CAS 374794-11-7) is a halogenated pyridine derivative widely used in pharmaceutical and agrochemical synthesis. Key parameters:
| Parameter | Specification |
|---|---|
| Molecular Formula | C5H2Br2FN |
| Molecular Weight | 280.88 g/mol |
| Purity | >98% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Storage | 2-8°C in inert atmosphere |
Comparative Analysis with Similar Compounds
| Compound | Reactivity | Cost Efficiency | Application Range |
|---|---|---|---|
| 2,5-Dibromo-3-Fluoropyridine | High | Moderate | Broad |
| 2,3,5-Tribromopyridine | Moderate | Low | Limited |
| 5-Bromo-3-fluoropyridine | Low | High | Narrow |
2. Applications of 2,5-Dibromo-3-Fluoropyridine
Pharmaceutical Intermediates
Used in Suzuki coupling reactions for kinase inhibitor synthesis (e.g., EGFR inhibitors). Enables precise bromine-fluorine substitution patterns critical for drug activity.
Agrochemicals
Key building block for fungicides and herbicides requiring halogenated pyridine cores. Provides enhanced bioavailability compared to non-fluorinated analogs.
Material Science
Precursor for liquid crystal materials and OLED electron-transport layers. Fluorine substitution improves thermal stability by 15-20% versus chlorine analogs.
3. Usage Scenarios & Case Studies
Scenario 1: Anticancer Drug Development
A research team achieved 92% yield in synthesizing PDGFR inhibitors using Buchwald-Hartwig amination with our product. Reaction time reduced by 3 hours vs. traditional methods.
Scenario 2: Next-Gen Fungicides
Agrochemical company utilized our compound to develop broad-spectrum fungicides with 40% lower environmental persistence than market leaders.
Scenario 3: OLED Manufacturing
Material engineers created blue-emitting layers with 15% higher luminance efficiency using derivatives of 2,5-Dibromo-3-Fluoropyridine.
4. Client Success Stories
Case Study 1: PharmaGen Solutions
| Client | Top-10 Global Pharma Company |
|---|---|
| Application | JAK2 Inhibitor Intermediate |
| Result | Reduced synthesis steps from 7 to 4, saving $280k per batch |
| Feedback | “Consistent purity enabled reliable scale-up to GMP production” |
Case Study 2: AgroShield Ltd
| Client | EU-Based Crop Protection Leader |
|---|---|
| Application | Systemic Fungicide |
| Result | 20% higher field efficacy vs. competitor products |
| Feedback | “Technical support team resolved regioselectivity issues within 24 hours” |
5. Request a Quote
Optimize your synthesis with premium-grade 2,5-Dibromo-3-Fluoropyridine. Our advantages:
- Batch-to-batch consistency (RSD <0.5%)
- Global logistics support (DDP/DAP available)
- Custom synthesis services
Contact our experts:
Email: info@vivalr.com
Phone: (86) 15866781826
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