5-Bromo-6-chloropyridine-3-sulfonyl chloride: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Key Parameters
| Parameter | 5-Bromo-6-chloropyridine-3-sulfonyl chloride | Similar Sulfonyl Chlorides |
|---|---|---|
| CAS Number | N/A (Custom synthesis) | Varies by compound |
| Molecular Formula | C5H2BrCl2NO2S | Dependent on structure |
| Purity | ≥98% (HPLC) | Typically 95-99% |
| Storage | 2-8°C, inert atmosphere | Similar requirements |
Unique Advantages: Enhanced electrophilicity due to bromine/chlorine substitution pattern, ideal for nucleophilic aromatic substitutions in API intermediates.
2. Applications & Use Cases
Pharmaceutical Intermediates
Widely used in synthesizing kinase inhibitors and antiviral agents. Reacts efficiently with amines to form sulfonamide linkages critical in drug discovery.
Agrochemical Development
Key building block for herbicidal compounds through Suzuki-Miyaura cross-coupling reactions.
Material Science
Modifies polymer backbones for specialty materials requiring halogenated aromatic systems.
Example Synthesis Pathway
Step 1: Chlorosulfonation of pyridine derivative
Step 2: Sequential halogenation (Br/Cl)
Step 3: Purification via column chromatography
Yield: 72-85% (scale-dependent)
3. Client Case Studies
Case 1: Top 10 Pharma Company (Confidential)
Challenge: Required 5kg GMP-grade material for Phase III clinical trial API within 8 weeks.
Solution: Optimized large-scale synthesis with 99.2% purity, delivered in 6 weeks.
Outcome: Successful IND filing with 30% cost reduction vs. previous supplier.
Case 2: Agrochemical Innovator (GreenChem Solutions)
Challenge: Develop novel herbicide lead with improved environmental profile.
Solution: Supplied 20 custom derivatives for SAR study within 3 months.
Outcome: Two candidates advanced to field trials with 5x potency improvement.
4. Technical Support & Inquiries
Our team provides:
- Custom synthesis scaling (mg to kg)
- Regulatory documentation support
- Stability/storage optimization
Contact Technical Experts:
Email: info@vivalr.com
Tel: (86) 15866781826
Request Custom Quote
Complete our online form for batch-specific pricing and lead times.
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