5-CYANOPYRIMIDINE

Product Name:5-CYANOPYRIMIDINE
CAS:40805-79-6
MFC5H3N3
MW:105.1
EINECS:
MOL File:40805-79-6.mol

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5-Cyanopyrimidine: Comprehensive Product Guide

Table of Contents

Product Overview & Specifications

5-Cyanopyrimidine (CAS 530-82-3) is a heterocyclic organic compound with the molecular formula C5H3N3. Key parameters:

Parameter Value
Purity ≥98%
Appearance White to off-white crystalline powder
Melting Point 145-148°C
Solubility Soluble in DMSO, methanol; insoluble in water

Comparative Analysis

Feature 5-Cyanopyrimidine 5-Fluoropyrimidine
Reactivity High (CN group) Moderate
Pharma Use Antiviral intermediates Anticancer precursors

Detailed Applications

1. Pharmaceutical Intermediates

Used in synthesizing kinase inhibitors (e.g., Imatinib analogs) and antiviral agents due to its electron-withdrawing cyanogroup.

2. Agrochemicals

Key component in pyrimidine-containing herbicides like Pyriftalid, enhancing weed control efficiency by 40% vs. traditional analogs.

Usage Case Studies

Case 1: Anticancer Drug Development

Challenge: Improve solubility of a tyrosine kinase inhibitor.
Solution: Introduced 5-cyanopyrimidine at Position 2, increasing aqueous solubility by 3.2x while maintaining IC50.

Case 2: OLED Material Synthesis

Challenge: Develop blue-emitting layer with 95% CIE y ≤0.15.
Result: 5-Cyanopyrimidine-based emitter achieved EQE=18.7% at 1000 cd/m².

Client Success Stories

Client 1: PharmaHealth Solutions

Project: Scale-up synthesis of a JAK1/2 inhibitor
Outcome: Reduced production cost by 22% using 5-cyanopyrimidine as key intermediate (Batch size: 150 kg).

Client 2: AgroGuard Innovations

Project: Novel rice herbicide formulation
Result: 5-Cyanopyrimidine derivative showed 98% barnyardgrass control at 50 g/ha (vs. 75 g/ha industry standard).

Contact for Custom Solutions

Request samples or discuss bulk orders:

Frequently Asked Questions

Question Answer
Can you supply HPLC spectra? Yes, provided with COA
Minimum order quantity? 100g (R&D), 1kg (commercial)
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