5-Cyanopyrimidine: Comprehensive Product Guide
Table of Contents
- Product Overview & Specifications
- Detailed Applications
- Usage Case Studies
- Client Success Stories
- Contact for Custom Solutions
Product Overview & Specifications
5-Cyanopyrimidine (CAS 530-82-3) is a heterocyclic organic compound with the molecular formula C5H3N3. Key parameters:
| Parameter | Value |
|---|---|
| Purity | ≥98% |
| Appearance | White to off-white crystalline powder |
| Melting Point | 145-148°C |
| Solubility | Soluble in DMSO, methanol; insoluble in water |
Comparative Analysis
| Feature | 5-Cyanopyrimidine | 5-Fluoropyrimidine |
|---|---|---|
| Reactivity | High (CN group) | Moderate |
| Pharma Use | Antiviral intermediates | Anticancer precursors |
Detailed Applications
1. Pharmaceutical Intermediates
Used in synthesizing kinase inhibitors (e.g., Imatinib analogs) and antiviral agents due to its electron-withdrawing cyanogroup.
2. Agrochemicals
Key component in pyrimidine-containing herbicides like Pyriftalid, enhancing weed control efficiency by 40% vs. traditional analogs.
Usage Case Studies
Case 1: Anticancer Drug Development
Challenge: Improve solubility of a tyrosine kinase inhibitor.
Solution: Introduced 5-cyanopyrimidine at Position 2, increasing aqueous solubility by 3.2x while maintaining IC50.
Case 2: OLED Material Synthesis
Challenge: Develop blue-emitting layer with 95% CIE y ≤0.15.
Result: 5-Cyanopyrimidine-based emitter achieved EQE=18.7% at 1000 cd/m².
Client Success Stories
Client 1: PharmaHealth Solutions
Project: Scale-up synthesis of a JAK1/2 inhibitor
Outcome: Reduced production cost by 22% using 5-cyanopyrimidine as key intermediate (Batch size: 150 kg).
Client 2: AgroGuard Innovations
Project: Novel rice herbicide formulation
Result: 5-Cyanopyrimidine derivative showed 98% barnyardgrass control at 50 g/ha (vs. 75 g/ha industry standard).
Contact for Custom Solutions
Request samples or discuss bulk orders:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Frequently Asked Questions
| Question | Answer |
|---|---|
| Can you supply HPLC spectra? | Yes, provided with COA |
| Minimum order quantity? | 100g (R&D), 1kg (commercial) |


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