1. Product Overview & Specifications

3-Bromo-5-hydroxypyridine (CAS 13466-43-8) is a halogenated pyridine derivative widely used in pharmaceutical and agrochemical synthesis.

2. Key Applications

Pharmaceutical Intermediates

Used in synthesizing kinase inhibitors and antiviral agents via Suzuki coupling reactions.

Agrochemical Building Block

Critical for creating herbicidal compounds with enhanced bioavailability.

Material Science

Facilitates production of coordination polymers for catalytic applications.

3. Usage Scenarios

Scenario 1: Anticancer Drug Synthesis

Step 1: Bromine-lithium exchange at -78°C
Step 2: Palladium-catalyzed cross-coupling
Step 3: Hydroxyl group protection

Scenario 2: Herbicide Development

Used in nucleophilic aromatic substitution to create pyridine-based herbicides.

4. Real-World Case Studies

Case 1: ABC Pharma (2023)

Developed PARP inhibitor using 3-Bromo-5-hydroxypyridine as key intermediate:
– 35% yield improvement vs. chloro analog
– Reduced reaction temperature by 20°C

Case 2: AgroChem Solutions (2022)

Created novel fungicide with 40% higher field efficacy:
– Enabled selective functionalization
– 15% reduction in production costs

5. Contact for Custom Solutions

Request bulk pricing or custom synthesis:
Email: info@vivalr.com
Phone: (86) 15866781826

Advantages:
– ISO-certified production
– Batch-to-batch consistency
– Technical support available