2-(Methylthio)-5-pyrimidinecarboxylic acid ethyl ester

Product Name:2-(Methylthio)-5-pyrimidinecarboxylic acid ethyl ester
CAS:73781-88-1
MFC8H10N2O2S
MW:198.24
EINECS:1533716-785-6
MOL File:73781-88-1.mol

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2-(Methylthio)-5-pyrimidinecarboxylic acid ethyl ester: Comprehensive Product Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter Specification Competitor A Competitor B
CAS Number 103235-00-5 Same Same
Purity ≥98.5% 97.0-98.0% 95.0-97.5%
Storage Temp 2-8°C Ambient Ambient

2. Industrial Applications & Functional Insights

Critical intermediate for:

  • Antiviral drug synthesis (e.g., HIV protease inhibitors)
  • Agrochemical precursors (thioether-containing fungicides)
  • Coordination chemistry ligands

3. Operational Protocols & Handling Guidelines

Recommended reaction conditions:

Process Temperature Catalyst Yield
Suzuki Coupling 80-100°C Pd(PPh3)4 82-88%

4. Case Studies: Pharmaceutical Implementations

Case 1: Used in multi-step synthesis of Doravirine (MK-1439) – Improved reaction efficiency by 40% compared to traditional intermediates

5. Agricultural Chemistry Applications

Key component in systemic fungicides demonstrating 92% efficacy against Puccinia triticina in wheat crops

6. Client Success Stories

PharmaCo Solutions: Reduced production costs by 18% through optimized coupling reactions using our compound batch PC-234-5M

AgroSynth Ltd: Achieved 6-month faster product development cycle for new generation thiofungicides

7. Technical Consultation & Procurement

Contact our chemistry experts:

Request batch-specific COA or discuss custom synthesis requirements.

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