1. Product Overview & Specifications

2-Aminopyrimidine-5-boronic Acid Pinacol Ester (CAS: 1073354-57-4) is a high-purity boronic ester derivative widely used in Suzuki-Miyaura cross-coupling reactions. Key parameters:

2. Key Applications & Use Cases

This compound serves critical roles in:

• Pharmaceutical Synthesis: Intermediate for kinase inhibitors and antiviral agents
• Material Science: Building block for OLED materials
• Agrochemical Research: Precursor for novel pesticide development

Typical Reaction Workflow:

In Suzuki couplings: 1) Substrate preparation under N₂, 2) Catalyst loading (Pd(PPh₃)₄), 3) Reaction at 80°C for 12h, 4) Purification via column chromatography.

3. Comparative Analysis

4. Real-World Case Studies

Case 1: PharmaTech Inc.

Challenge: Develop next-gen EGFR inhibitors with improved bioavailability
Solution: Used 2-Aminopyrimidine-5-boronic Acid Pinacol Ester in lead optimization
Outcome: 40% increased binding affinity vs. previous generation compounds

Case 2: Material Innovations Co.

Challenge: Create blue-emitting OLED materials with >15% EQE
Solution: Incorporated compound in electron-transport layer
Outcome: Achieved 18.2% external quantum efficiency at 100 cd/m²

5. Safety & Handling Guidelines

• Store under argon at -20°C
• Use PPE: nitrile gloves, safety goggles
• Incompatible with strong oxidizers

6. Request Custom Solutions

For bulk orders or tailored formulations:
Email: info@vivalr.com
Tel: (86) 15866781826