2-Methoxypyridne-4-boronic acid

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Complete Guide to 2-Methoxypyridine-4-boronic Acid

1. Product Overview & Specifications

Parameter Specification
CAS Number 1072931-77-4
Molecular Formula C₆H₈BNO₃
Molecular Weight 168.95 g/mol
Purity ≥97% (HPLC)
Appearance White to off-white crystalline powder
Storage Conditions 2-8°C in inert atmosphere

2. Key Applications & Industrial Uses

Pharmaceutical Development

Critical intermediate for kinase inhibitors and anticancer agents

Organic Synthesis

Suzuki-Miyaura cross-coupling reactions for aryl-aryl bond formation

Material Science

Building block for OLED materials and conductive polymers

3. Technical Comparison with Similar Compounds

Compound Reactivity Solubility Typical Yield
2-Methoxypyridine-4-boronic acid High Soluble in THF, DMF 85-92%
4-Methoxyphenylboronic acid Moderate Soluble in EtOH 75-82%
3-Methoxypyridine-5-boronic acid Low Partial in DCM 60-68%

4. Detailed Usage Scenarios

Scenario 1: Suzuki Coupling in Drug Synthesis

Reaction conditions: Pd(PPh3)4 catalyst, Na2CO3 base, DME/H2O solvent system at 80°C

Scenario 2: Material Polymerization

Co-polymerization with thiophene derivatives for conductive materials

5. Verified Customer Case Studies

Case Study 1: PharmaSynth Co., Ltd. (2024)

Application: Developed novel kinase inhibitor using 50kg batch

Result: Achieved 89% coupling efficiency in final API synthesis

Case Study 2: MaterialInnovate Inc. (2023)

Application: OLED emitter material development

Result: 15% improvement in device efficiency vs previous formulations

6. Procurement & Inquiry Guidance

Available package sizes: 1g, 5g, 25g, 100g, 1kg

Lead time: 2-3 weeks for standard orders

Contact technical team:

  • Email: info@vivalr.com
  • Tel: (86) 15866781826

Request SDS and COA documents for batch-specific analysis

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