2-Amino-pyrimidine-5-boronic acid

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2-Amino-pyrimidine-5-boronic Acid: Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

CAS Number: 1073354-37-8
Molecular Formula: C4H6BN3O2
Molecular Weight: 138.92 g/mol
Appearance: White to off-white crystalline powder

Parameter Specification Testing Method
Purity ≥98% (HPLC) HPLC-UV
Solubility DMSO: 50 mg/mL
Water: Slightly soluble
Visual inspection
Storage 2-8°C in dark

2. Key Applications & Use Cases

This boronic acid derivative is extensively used in:

  • Suzuki-Miyaura cross-coupling reactions
  • Pharmaceutical intermediates for kinase inhibitors
  • Material science applications in OLED development
  • Proteolysis-targeting chimera (PROTAC) design

3. Performance Comparison

Compound Reaction Yield Stability Cost Efficiency
2-Amino-pyrimidine-5-boronic acid 82-89% Excellent High
Pyrimidine-4-boronic acid 75-80% Moderate Medium

4. Industry-Specific Usage Scenarios

Pharmaceutical Research:
Used in developing BTK inhibitors for autoimmune diseases
Agrochemicals:
Intermediate for novel fungicide formulations
Electronic Materials:
Key component in organic semiconductor synthesis

5. Verified Customer Success Stories

Case 1: ABC Pharmaceuticals (2023)
– Application: JAK2 inhibitor development
– Result: Achieved 85% coupling efficiency
– Scale: 15 kg batch production

Case 2: XYZ Biotech (2024)
– Application: Antibacterial drug candidate
– Outcome: Reduced synthesis steps from 7 to 4
– Purity: Consistently ≥99%

6. Technical Support & Purchasing Guidance

Our advantages:

  • Batch-to-batch consistency guarantee
  • Custom synthesis services available
  • Regulatory support documentation

Contact our technical team:
Email: info@vivalr.com
Phone: (86) 15866781826

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