2-Methanesulfonyl-4,6-dimethoxypyrimidine

Table of Contents

• Product Overview & Specifications
• Applications in Agrochemicals & Pharmaceuticals
• Operational Guidelines & Safety Protocols
• Case Study: Crop Protection Agent Synthesis
• Client Success Stories
• Request Customized Solutions

1. Product Overview & Specifications

Chemical Name: 2-Methanesulfonyl-4,6-dimethoxypyrimidine

CAS No.: 145783-13-7

Molecular Formula: C₇H₁₀N₂O₄S

Molecular Weight: 218.23 g/mol

Comparative Analysis with Analogues

2. Applications in Agrochemicals & Pharmaceuticals

Key Industrial Uses:

• Herbicide Intermediates: Critical building block for sulfonylurea herbicides like bensulfuron-methyl
• Pharmaceutical Synthesis: Used in kinase inhibitor development for oncology therapeutics
• Chemical Research: Versatile scaffold for Suzuki-Miyaura cross-coupling reactions

3. Operational Guidelines & Safety Protocols

Handling Recommendations:

1. Store at 2-8°C in inert atmosphere (argon/nitrogen)
2. Use PPE including nitrile gloves and chemical goggles
3. Reaction conditions: Typically used in THF/DMF at 60-80°C under basic catalysis

4. Case Study: Crop Protection Agent Synthesis

Challenge: Develop cost-effective pathway for bensulfuron-methyl precursor

Solution: Utilized 2-Methanesulfonyl-4,6-dimethoxypyrimidine in nucleophilic aromatic substitution

Result: 92% yield achieved with 99.5% HPLC purity

5. Client Success Stories

Case 1: European Agrochemical Manufacturer

• Background: Needed GMP-compliant intermediate for EU regulatory submission
• Outcome: Reduced production costs by 18% through optimized synthetic route

Case 2: Asian Pharmaceutical Company

• Challenge: Scale-up from lab to 500kg batch production
• Solution: Custom purification protocol development
• Result: Achieved consistent ≥99% purity at commercial scale

6. Request Customized Solutions

Contact our technical team for:

• Bulk pricing (100kg+ quantities available)
• Custom synthesis with strict IP protection
• Regulatory support (REACH, FDA DMF filings)

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Phone: (86) 15866781826