Comprehensive Guide to 3-Amino-Isonicotinic Acid Methyl Ester
Table of Contents
- Product Overview & Specifications
- Key Applications
- Usage Guidelines
- Industry Case Studies
- Contact for Custom Solutions
Product Overview & Specifications
3-Amino-Isonicotinic Acid Methyl Ester (CAS 131747-25-6) is a specialized heterocyclic compound widely used in pharmaceutical synthesis and agrochemical research.
| Parameter | Specification | Comparison: Similar Esters |
|---|---|---|
| CAS Number | 131747-25-6 | 3-Amino-Benzoic Acid Methyl Ester (CAS 52127-84-3) |
| Molecular Formula | C7H8N2O2 | C8H9NO2 |
| Purity | ≥98% (HPLC) | Typically 95-97% in commercial grades |
| Solubility | Soluble in DMSO, Methanol | Limited solubility in polar solvents |
Key Applications
Pharmaceutical Intermediates
Critical component in synthesizing anti-tuberculosis agents and kinase inhibitors. Enables precise molecular modifications in lead compound optimization.
Agrochemical Development
Used in creating novel fungicides with improved leaf adhesion and rainfastness properties. Particularly effective against Phytophthora infestans.
Coordination Chemistry
Acts as polydentate ligand in transition metal complexes for catalytic applications and materials science research.
Usage Guidelines
Recommended Protocols
- Handling: Use under inert atmosphere (N2 or Ar) for moisture-sensitive reactions
- Storage: Maintain at 2-8°C in sealed amber glass containers
- Reaction Conditions: Optimal performance at 60-80°C in DMF or THF solvents
Safety Information
| Hazard Code | Precaution | First Aid |
|---|---|---|
| Xi | Wear nitrile gloves and safety goggles | Flush eyes with water for 15 minutes if contacted |
Industry Case Studies
Case Study 1: Antiviral Drug Development
Client: European Pharma Research Group
Challenge: Improve bioavailability of NNRTI candidates
Solution: Used as key building block in scaffold modification
Result: Achieved 40% improvement in water solubility
Case Study 2: Next-Gen Fungicides
Client: Global Agrochemical Manufacturer
Challenge: Resistance management in Oomycete pathogens
Solution: Incorporated into novel SDHI fungicide design
Result: 98% efficacy at 50% reduced application rate
Contact for Custom Solutions
Optimize your synthesis with our technical expertise:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Why Choose Our Product?
– Batch-to-batch consistency (RSD <0.5%)
– Custom purity grades (98-99.9%)
– Technical support from PhD chemists


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