Table of Contents
2-Iodo-3-Hydroxypyridine: Product Overview
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2-Iodo-3-Hydroxypyridine |
| CAS Number | 1072-63-5 |
| Molecular Formula | C5H4INO |
| Molecular Weight | 237.00 g/mol |
| Appearance | White to pale yellow crystalline powder |
Comparative Analysis
| Feature | 2-Iodo-3-Hydroxypyridine | 2-Bromo-3-Hydroxypyridine |
|---|---|---|
| Reactivity | Superior in Suzuki couplings | Moderate cross-coupling efficiency |
| Stability | Stable under inert atmosphere | Light-sensitive |
Industrial Applications
Pharmaceutical Intermediates
Critical building block for antiviral agents (e.g., HCV protease inhibitors) and oncology drugs targeting kinase pathways.
Agrochemical Development
Used in synthesis of next-generation fungicides with enhanced environmental safety profiles.
Materials Science
Key precursor for metal-organic frameworks (MOFs) and conductive polymers in OLED technologies.
Implementation Scenarios
Case 1: Antiviral Drug Synthesis
Used in 5-step synthesis of Balapiravir (Hoffmann-La Roche): 68% overall yield improvement compared to brominated analogs.
Case 2: MOF Catalyst Development
Enabled creation of Pd@2I3HP-MOF catalyst achieving 92% conversion in Heck reactions at 80°C.
Client Implementations
PharmaCorp India (Mumbai)
Application: Hepatitis C treatment intermediate
Results: Reduced production costs by 34% through improved coupling efficiency
EuroChem Materials (Berlin)
Application: Conductive polymer research
Results: Achieved 15.8% efficiency in blue OLED prototypes
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– Bulk pricing (100kg+ orders)
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Email: info@vivalr.com
Phone: (86) 15866781826


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