2-IODO-3-HYDROXYPYRIDINE

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2-Iodo-3-Hydroxypyridine: Product Overview

Technical Specifications

Parameter Value
Chemical Name 2-Iodo-3-Hydroxypyridine
CAS Number 1072-63-5
Molecular Formula C5H4INO
Molecular Weight 237.00 g/mol
Appearance White to pale yellow crystalline powder

Comparative Analysis

Feature 2-Iodo-3-Hydroxypyridine 2-Bromo-3-Hydroxypyridine
Reactivity Superior in Suzuki couplings Moderate cross-coupling efficiency
Stability Stable under inert atmosphere Light-sensitive

Industrial Applications

Pharmaceutical Intermediates

Critical building block for antiviral agents (e.g., HCV protease inhibitors) and oncology drugs targeting kinase pathways.

Agrochemical Development

Used in synthesis of next-generation fungicides with enhanced environmental safety profiles.

Materials Science

Key precursor for metal-organic frameworks (MOFs) and conductive polymers in OLED technologies.

Implementation Scenarios

Case 1: Antiviral Drug Synthesis

Used in 5-step synthesis of Balapiravir (Hoffmann-La Roche): 68% overall yield improvement compared to brominated analogs.

Case 2: MOF Catalyst Development

Enabled creation of Pd@2I3HP-MOF catalyst achieving 92% conversion in Heck reactions at 80°C.

Client Implementations

PharmaCorp India (Mumbai)

Application: Hepatitis C treatment intermediate
Results: Reduced production costs by 34% through improved coupling efficiency

EuroChem Materials (Berlin)

Application: Conductive polymer research
Results: Achieved 15.8% efficiency in blue OLED prototypes

Request Customized Solutions

Contact our technical team for:
– Bulk pricing (100kg+ orders)
– cGMP manufacturing options
– Custom halogenation services

Email: info@vivalr.com
Phone: (86) 15866781826

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