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2-Amino-3,5-dichloropyridine: Technical Guide & Industry Applications
Table of Contents
- Product Specifications & Comparative Analysis
- Industrial Applications
- Operational Guidelines
- Case Studies
- Client Success Stories
- Procurement Consultation
1. Product Specifications & Comparative Analysis
| Parameter | 2-Amino-3,5-dichloropyridine | Analogous Compounds |
|---|---|---|
| CAS Number | 4214-74-8 | 313535-01-2 (3,6-dichloro variant) |
| Molecular Formula | C5H4Cl2N2 | C5H4Cl2N2 (isomeric differences) |
| Melting Point | 81-83°C | 125°C (2,5-dichloro-3-aminopyridine) |
| Water Solubility | Insoluble | Variable in halogenated analogs |
2. Industrial Applications
Core Utilization Sectors
- Pharmaceutical Intermediates: Key precursor in antihypertensive APIs
- Agrochemical Production: Chlorinated pyridine derivatives for fungicides
- Organic Synthesis: Building block for heterocyclic compounds
Performance Advantages
| Application | Benefit | Typical Yield Improvement |
|---|---|---|
| Cross-coupling Reactions | Enhanced regioselectivity | 12-15% vs non-chlorinated analogs |
| Catalytic Hydrogenation | Improved catalyst lifetime | 30-40 cycles stability |
3. Operational Guidelines
Handling Protocols
- Storage: Maintain at 2-8°C in inert atmosphere
- Reactivity: Avoid strong oxidizers & bases
- PPE Requirements: Chem-resistant gloves & vapor masks
4. Case Studies
Pharmaceutical Intermediate Production
| Client | Application | Outcome |
|---|---|---|
| Shanghai Yuanye Bio-Tech | Antiviral drug intermediate synthesis | 15% cost reduction in final API |
| Solarbio Science | High-purity analytical standards | 99.7% HPLC purity achieved |
5. Client Success Stories
Case 1: Agrochemical Manufacturer
Client: Shandong Chongcheng Energy
Challenge: Develop persistent fungicide with lower toxicity
Solution: 2-Amino-3,5-dichloropyridine based formulation
Results: 40% improved field efficacy, EPA Category IV certification
Case 2: Contract Research Organization
Client: Beijing Solarbio
Project: Scale-up novel kinase inhibitor
Role: Critical coupling reagent in lead compound
Achievement: Successful Phase I clinical trial material production
6. Procurement Consultation
Technical Support Services
- Custom synthesis from lab to production scale
- Regulatory documentation support (REACH, TSCA)
- Quality assurance protocols development
Contact Our Experts
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