1. Product Specifications & Comparative Analysis

Synonyms: 2-Amino-4-methyl-5-bromopyridine, 5-Bromo-4-methylpyridin-2-amine

2. Key Applications

Pharmaceutical Intermediate

Critical building block for synthesizing kinase inhibitors and targeted cancer therapies.

Agrochemical Development

Key precursor in creating advanced crop protection agents with enhanced bioavailability.

Material Science

Used in coordination chemistry for creating luminescent metal-organic frameworks (MOFs).

3. Usage Guidelines

Handling Protocols

• Use inert atmosphere for moisture-sensitive reactions
• Recommended solvent systems: DMF/DMSO (polar aprotic)
• Optimal reaction temperature: 60-80°C

Derivatization Examples

1. Buchwald-Hartwig amination for heterocyclic systems
2. Suzuki-Miyaura cross-coupling reactions
3. Directed ortho-metalation reactions

4. Industrial Case Studies

Case 1: Antiviral Drug Development

Used as key intermediate in synthesis of broad-spectrum antiviral agents, achieving 92% yield in final coupling step.

Case 2: OLED Materials

Enabled creation of electron-transport layers with 15% improved luminance efficiency in display technologies.

5. Client Success Stories

MedChemExpress (MCE)

Supplied 25g batches (HY-17562) for high-throughput screening of kinase inhibitors, maintaining >99.7% purity across 18-month stability studies.

Shanghai Macklin Biochemical

Custom-synthesized 2-aminonicotinonitrile derivatives for specialty chemical applications, reducing production costs by 22% through optimized bromination protocols.

6. Request Customized Solutions

Our technical team provides:

• Bulk synthesis (100g-10kg scale)
• Custom derivatization services
• Regulatory support (REACH, TSCA)

Contact our specialists:
Email: info@vivalr.com
Tel: (86) 15866781826