4,4-Difluoropiperidine Hydrochloride: Technical Guide & Supplier Insights
Table of Contents
1. Product Overview & Specifications
4,4-Difluoropiperidine hydrochloride (CAS 1146766-41-8) is a fluorinated piperidine derivative with molecular formula C5H8ClF2N. Key parameters:
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Purity | ≥98.5% | 97.0% | 95.5% |
| Melting Point | 192-195°C | 188-192°C | 185-190°C |
| Solubility | Water >50 mg/mL | 30 mg/mL | 25 mg/mL |
2. Key Applications & Industrial Uses
Primary applications in pharmaceutical intermediates:
- Kinase inhibitor synthesis
- Neurological drug candidates
- Radioactive tracer development
3. Implementation Case Studies
Case 1: Oncology Drug Development
Client: Top 10 Global Pharma Company
Application: PARP inhibitor intermediate synthesis
Result: 22% yield improvement vs. traditional piperidine derivatives
Case 2: PET Tracer Production
Client: Medical Imaging Research Institute
Application: 18F-labeled compound synthesis
Result: 93.4% radiochemical purity achieved
4. Performance Comparison Table
| Feature | Our Product | Standard Piperidine HCl |
|---|---|---|
| Metabolic Stability | t1/2 = 6.7h | t1/2 = 2.1h |
| Lipophilicity (LogP) | 1.2 | 0.3 |
5. Supplier Inquiry & Custom Solutions
Contact our technical team for:
- Batch-specific COA
- Custom fluorination services
- GMP-grade manufacturing
Email: info@vivalr.com
Tel: (86) 15866781826
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