Carbonic Acid, Methyl 2,2,2-Trifluoroethyl Ester Cas 156783-95-8

Chemical Name: Carbonic acid, Methyl 2,2,2-trifluoroethyl ester
CAS No.: 156783-95-8
Molecular Fomula: C4H5F3O3
Molecular weight: 158.08
Appearance: Colorless clear liquid

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Carbonic Acid, Methyl 2,2,2-Trifluoroethyl Ester (CAS 156783-95-8): Comprehensive User Guide

1. Product Overview & Specifications

Carbonic Acid, Methyl 2,2,2-Trifluoroethyl Ester (CAS 156783-95-8) is a fluorinated ester compound widely used in organic synthesis, pharmaceutical intermediates, and specialty chemical manufacturing. Below are its key specifications:

Parameter Specification
Chemical Name Carbonic Acid, Methyl 2,2,2-Trifluoroethyl Ester
CAS Number 156783-95-8
Molecular Formula C4H5F3O3
Molecular Weight 170.08 g/mol
Appearance Colorless to pale yellow liquid
Purity ≥98% (GC)
Boiling Point 85-87°C at 760 mmHg
Density 1.35 g/cm³
Solubility Miscible with organic solvents (e.g., DCM, THF)

Comparative Advantages

Feature This Product Similar Esters
Thermal Stability High (>150°C) Moderate (100-120°C)
Fluorine Content 3 Fluorine atoms 1-2 Fluorine atoms
Reactivity High (due to trifluoroethyl group) Standard

2. Key Applications

  • Pharmaceutical Intermediates: Used in synthesizing trifluoroethyl-containing APIs for antiviral and anticancer drugs.
  • Agrochemicals: Key component in fluorinated pesticides and herbicides.
  • Electronics: Serves as a solvent in lithium-ion battery electrolytes.
  • Polymer Chemistry: Building block for fluorinated polymers with enhanced chemical resistance.

3. Usage Guidelines

Handling & Storage

  • Store in a cool, dry place (2-8°C) under inert gas (N₂/Ar).
  • Use corrosion-resistant equipment (e.g., glass or PTFE-lined containers).

Reaction Conditions

  • Optimal temperature: 40-60°C in anhydrous environments.
  • Compatible with catalysts like DBU or DMAP.

4. Industry Use Cases

Case 1: Antiviral Drug Synthesis

Process: Reacted with nucleoside analogs to introduce trifluoroethyl groups, improving metabolic stability. Yield: 82%.

Case 2: Fluorinated Herbicide Production

Process: Used as an alkylating agent in a Grignard reaction. Reduced reaction time by 30% compared to alternatives.

5. Client Success Stories

Client A: Top-tier Pharma Company (Europe)

  • Challenge: Needed a stable intermediate for a Phase III oncology drug.
  • Solution: Supplied 98.5% purity product under cGMP conditions.
  • Result: Accelerated scale-up by 6 months; FDA approval secured in 2023.

Client B: Agrochemical Manufacturer (USA)

  • Challenge: Required cost-effective fluorination for a new herbicide.
  • Solution: Customized bulk delivery with 24/7 technical support.
  • Result: 20% cost reduction and 15% higher field efficacy.

6. Contact for Inquiries

Request a quote, sample, or technical dossier:

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