Allyl Chloroformate (CAS 2937-50-0): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Basic Properties
- CAS Number: 2937-50-0
- Molecular Formula: C4H5ClO2
- Molecular Weight: 120.53 g/mol
- Appearance: Colorless to pale yellow liquid
- Density: 1.14 g/cm³ at 25°C
- Boiling Point: 110-112°C
- Flash Point: 23°C (closed cup)
Comparative Analysis
| Parameter | Allyl Chloroformate | Methyl Chloroformate | Ethyl Chloroformate |
|---|---|---|---|
| Reactivity | High (allyl group) | Moderate | Moderate |
| Volatility | Medium | High | Medium |
| Application Range | Pharma, Polymers | Agrochemicals | Fine Chemicals |
2. Key Applications & Use Cases
Pharmaceutical Intermediates
Widely used in synthesizing β-lactam antibiotics and carbamate prodrugs due to its superior leaving group properties.
Agrochemical Production
Essential for creating allyl-based pesticides with enhanced environmental stability and targeted pest control.
Polymer Chemistry
Enables synthesis of functionalized polycarbonates and specialty resins with improved thermal resistance (up to 200°C).
3. Industry Case Studies
Case 1: Cephalosporin Antibiotic Production
A European pharma manufacturer achieved 18% yield improvement in cefotaxime synthesis through optimized allyl chloroformate coupling reactions.
Case 2: Low-VOC Agricultural Formulations
Developed 40% reduced-emission fungicide by replacing traditional carbonyl sources with allyl chloroformate derivatives.
4. Client Success Stories
Client A: Top 10 Global Pharma Company
- Application: Prodrug synthesis for hepatitis C treatment
- Result: Reduced reaction steps from 5 to 3 stages
- Purity Achieved: 99.8% (HPLC)
Client B: Specialty Polymer Manufacturer
- Application: Flame-retardant polycarbonate production
- Result: Achieved UL94 V-0 rating at 1.6mm thickness
- Capacity: 15 MT/month continuous production
5. Request Customized Solutions
Our technical team provides:
- Batch-specific Certificates of Analysis
- Custom synthesis (1kg to ton-scale)
- Regulatory support (REACH, TSCA compliant)
Contact our specialists for formulation optimization or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826



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