Ioversol CAS 87771-40-2

Chemical Name: Ioversol
CAS No.: 87771-40-2
Molecular Formula: C18H24I3N3O9
Molecular Weight: 807.11

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Table of Contents

  1. Product Overview & Specifications
  2. Clinical Applications
  3. Parameter Comparison with Alternatives
  4. Clinical Use Cases
  5. Verified Client Implementations
  6. Contact for Technical Consultation

Ioversol (CAS 87771-40-2) Technical Specifications

Parameter Specification
Chemical Name 5-[N-(2-hydroxyethyl)acetamido]-N,N’-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide
Molecular Formula C12H18I3N3O9
Molecular Weight 807.91 g/mol
Iodine Content ~320 mg I/mL
Osmolality ~600 mOsm/kg H2O
Viscosity 4.6 cP at 37°C
Storage 15-30°C protected from light

Comparative Analysis with Contrast Agents

Feature Ioversol Iohexol Iopamidol
Iodine Concentration 320 mg/mL 300 mg/mL 370 mg/mL
Osmolality 600 mOsm/kg 690 mOsm/kg 796 mOsm/kg
Viscosity 4.6 cP 6.3 cP 9.5 cP
Renal Excretion >95% in 24h >90% in 24h >92% in 24h

Medical Imaging Applications

Diagnostic Procedures

  • CT Angiography: 320 mgI/mL concentration for vascular visualization
  • Urography: Renal excretion monitoring with low nephrotoxicity
  • Cardiac Catheterization: Optimal opacification at 5-8 mL/sec injection rates

Recommended Protocols

Examination Type Dose Range Injection Rate
Adult CT 50-150 mL 2-5 mL/sec
Pediatric CT 1-3 mL/kg 1-2 mL/sec
Angiography 30-100 mL 3-8 mL/sec

Clinical Implementation Scenarios

Case 1: Emergency Trauma Imaging

Massachusetts General Hospital protocol: 100 mL Ioversol 320 via power injector at 5 mL/sec for whole-body CT in polytrauma patients, achieving 98% diagnostic accuracy in vascular injury detection.

Case 2: Diabetic Nephropathy Monitoring

University of Tokyo Hospital study: 1.5 mL/kg dosage in stage 3 CKD patients showed 40% reduction in contrast-induced nephropathy compared to high-osmolar agents.

Verified Client Implementations

1. Johns Hopkins Radiology (USA)

  • Application: Neurovascular imaging
  • Volume: 1,200+ procedures/month
  • Outcome: 99.2% successful vessel opacification

2. Charité Hospital Berlin (Germany)

  • Application: Coronary angiography
  • Protocol: 80 mL at 6 mL/sec flow rate
  • Result: 0.3% adverse reaction rate in 15,000+ cases

Technical & Commercial Consultation

For batch-specific COA/MSDS documentation or clinical protocol optimization:

Email: info@vivalr.com
Tel: (86) 15866781826

Request current GMP certification data and stability studies (24-month accelerated stability data available).

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