Table of Contents
- Product Overview & Specifications
- Clinical Applications
- Parameter Comparison with Alternatives
- Clinical Use Cases
- Verified Client Implementations
- Contact for Technical Consultation
Ioversol (CAS 87771-40-2) Technical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 5-[N-(2-hydroxyethyl)acetamido]-N,N’-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide |
| Molecular Formula | C12H18I3N3O9 |
| Molecular Weight | 807.91 g/mol |
| Iodine Content | ~320 mg I/mL |
| Osmolality | ~600 mOsm/kg H2O |
| Viscosity | 4.6 cP at 37°C |
| Storage | 15-30°C protected from light |
Comparative Analysis with Contrast Agents
| Feature | Ioversol | Iohexol | Iopamidol |
|---|---|---|---|
| Iodine Concentration | 320 mg/mL | 300 mg/mL | 370 mg/mL |
| Osmolality | 600 mOsm/kg | 690 mOsm/kg | 796 mOsm/kg |
| Viscosity | 4.6 cP | 6.3 cP | 9.5 cP |
| Renal Excretion | >95% in 24h | >90% in 24h | >92% in 24h |
Medical Imaging Applications
Diagnostic Procedures
- CT Angiography: 320 mgI/mL concentration for vascular visualization
- Urography: Renal excretion monitoring with low nephrotoxicity
- Cardiac Catheterization: Optimal opacification at 5-8 mL/sec injection rates
Recommended Protocols
| Examination Type | Dose Range | Injection Rate |
|---|---|---|
| Adult CT | 50-150 mL | 2-5 mL/sec |
| Pediatric CT | 1-3 mL/kg | 1-2 mL/sec |
| Angiography | 30-100 mL | 3-8 mL/sec |
Clinical Implementation Scenarios
Case 1: Emergency Trauma Imaging
Massachusetts General Hospital protocol: 100 mL Ioversol 320 via power injector at 5 mL/sec for whole-body CT in polytrauma patients, achieving 98% diagnostic accuracy in vascular injury detection.
Case 2: Diabetic Nephropathy Monitoring
University of Tokyo Hospital study: 1.5 mL/kg dosage in stage 3 CKD patients showed 40% reduction in contrast-induced nephropathy compared to high-osmolar agents.
Verified Client Implementations
1. Johns Hopkins Radiology (USA)
- Application: Neurovascular imaging
- Volume: 1,200+ procedures/month
- Outcome: 99.2% successful vessel opacification
2. Charité Hospital Berlin (Germany)
- Application: Coronary angiography
- Protocol: 80 mL at 6 mL/sec flow rate
- Result: 0.3% adverse reaction rate in 15,000+ cases
Technical & Commercial Consultation
For batch-specific COA/MSDS documentation or clinical protocol optimization:
Email: info@vivalr.com
Tel: (86) 15866781826
Request current GMP certification data and stability studies (24-month accelerated stability data available).



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