Glycine ethyl ester hydrochloride CAS 623-33-6

CAS No.:623-33-6
Chemical Name: Glycine ethyl ester hydrochloride
CAS No.: 623-33-6
Appearance: White needle crystal
Assay:≥99.0%

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Table of Contents

Glycine Ethyl Ester Hydrochloride (CAS 623-33-6): Technical Specifications

Basic Parameters

Parameter Specification
CAS Number 623-33-6
Molecular Formula C4H10ClNO2
Molecular Weight 139.58 g/mol
Appearance White crystalline powder
Purity ≥98% (HPLC)
Melting Point 144-148°C
Solubility Water: 50 mg/mL; Ethanol: Slightly soluble

Comparative Analysis

Feature Glycine Ethyl Ester HCl Similar Amino Acid Esters
Storage Stability 24 months at 2-8°C Typically 12-18 months
Pharma-grade Pricing $85/kg (Bulk) $95-$120/kg
Reaction Efficiency 92-95% yield 85-90% average

Industrial Applications & Functional Uses

Pharmaceutical Manufacturing

Critical intermediate for:

  • Antiviral drug synthesis (e.g., HIV protease inhibitors)
  • Antibiotic production
  • Neurological drug development

Biochemical Research

  • Peptide synthesis protection/deprotection agent
  • Enzyme substrate studies
  • Cell culture media component

Industrial Synthesis

  • Surfactant production
  • Polymer modification agent
  • Agrochemical precursors

Implementation Case Studies

Pharmaceutical Case: Antiretroviral Drug Production

Challenge: Improve synthesis efficiency of Darunavir intermediate
Solution: Optimized glycine ethyl ester HCl coupling at 0.8 molar ratio
Result: 18% cost reduction, 99.2% HPLC purity

Research Application: Peptide Library Development

Challenge: Prevent racemization during solid-phase synthesis
Solution: Used as temporary protecting group
Result: 97% chiral purity achieved

Verified Client Implementations

Client 1: Top-10 Global Pharma Company

Application: Continuous flow synthesis of oncology APIs
Volume: 2.5MT annual consumption
Feedback: “Consistent batch-to-batch quality enabled scale-up success”

Client 2: Biotech Startup (Peptide Therapeutics)

Application: GMP-grade peptide drug manufacturing
Result: Achieved FDA approval for NDA submission
Testimonial: “Critical component in our cGMP workflow”

Client 3: Agrochemical Leader

Application: Herbicide intermediate synthesis
Outcome: 40% faster reaction kinetics vs previous reagents
Metric: Reduced production costs by $1.2M annually

Request Customized Solutions

Contact our technical team for:

  • Bulk pricing (100kg+ orders)
  • GMP certification support
  • Custom synthesis protocols

Email: info@vivalr.com
Phone: (86) 15866781826

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