Table of Contents
- Product Overview & Specifications
- Key Applications & Uses
- Industry Case Studies
- Client Success Stories
- Request Customized Solutions
Glycine Ethyl Ester Hydrochloride (CAS 623-33-6): Technical Specifications
Basic Parameters
| Parameter | Specification |
|---|---|
| CAS Number | 623-33-6 |
| Molecular Formula | C4H10ClNO2 |
| Molecular Weight | 139.58 g/mol |
| Appearance | White crystalline powder |
| Purity | ≥98% (HPLC) |
| Melting Point | 144-148°C |
| Solubility | Water: 50 mg/mL; Ethanol: Slightly soluble |
Comparative Analysis
| Feature | Glycine Ethyl Ester HCl | Similar Amino Acid Esters |
|---|---|---|
| Storage Stability | 24 months at 2-8°C | Typically 12-18 months |
| Pharma-grade Pricing | $85/kg (Bulk) | $95-$120/kg |
| Reaction Efficiency | 92-95% yield | 85-90% average |
Industrial Applications & Functional Uses
Pharmaceutical Manufacturing
Critical intermediate for:
- Antiviral drug synthesis (e.g., HIV protease inhibitors)
- Antibiotic production
- Neurological drug development
Biochemical Research
- Peptide synthesis protection/deprotection agent
- Enzyme substrate studies
- Cell culture media component
Industrial Synthesis
- Surfactant production
- Polymer modification agent
- Agrochemical precursors
Implementation Case Studies
Pharmaceutical Case: Antiretroviral Drug Production
Challenge: Improve synthesis efficiency of Darunavir intermediate
Solution: Optimized glycine ethyl ester HCl coupling at 0.8 molar ratio
Result: 18% cost reduction, 99.2% HPLC purity
Research Application: Peptide Library Development
Challenge: Prevent racemization during solid-phase synthesis
Solution: Used as temporary protecting group
Result: 97% chiral purity achieved
Verified Client Implementations
Client 1: Top-10 Global Pharma Company
Application: Continuous flow synthesis of oncology APIs
Volume: 2.5MT annual consumption
Feedback: “Consistent batch-to-batch quality enabled scale-up success”
Client 2: Biotech Startup (Peptide Therapeutics)
Application: GMP-grade peptide drug manufacturing
Result: Achieved FDA approval for NDA submission
Testimonial: “Critical component in our cGMP workflow”
Client 3: Agrochemical Leader
Application: Herbicide intermediate synthesis
Outcome: 40% faster reaction kinetics vs previous reagents
Metric: Reduced production costs by $1.2M annually
Request Customized Solutions
Contact our technical team for:
- Bulk pricing (100kg+ orders)
- GMP certification support
- Custom synthesis protocols
Email: info@vivalr.com
Phone: (86) 15866781826



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