Coenzyme A CAS 85-61-0

Chemical Name: Coenzyme A
CAS No.: 85-61-0
Appearance: White powder
Assay:99%

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Coenzyme A (CAS 85-61-0) Comprehensive Guide

1. Product Overview & Specifications

Coenzyme A (CAS 85-61-0) is a crucial cofactor in cellular metabolism with the molecular formula C21H36N7O16P3S and molecular weight 767.53 g/mol.

Parameter Specification
Purity ≥95% (HPLC)
Appearance White lyophilized powder
Solubility 10 mg/mL in water
Storage -20°C in dry conditions
Shelf Life 24 months

2. Key Applications & Biological Functions

Essential for:

  • Fatty acid synthesis/oxidation
  • Citric acid cycle regulation
  • Acetyl group transfer reactions
  • Detoxification pathways
  • Enzyme activation (e.g., acetyltransferases)

3. Comparative Analysis

Feature Coenzyme A Acetyl-CoA Pantethine
Core Function Universal acyl carrier Acetyl group transfer Precursor molecule
Stability ⭐⭐⭐⭐ ⭐⭐⭐ ⭐⭐⭐⭐⭐
Research Applications Broad-spectrum Specific metabolic studies Supplement research

4. Usage Guidelines

Optimal Concentrations:

  • Cell Culture: 1-5 μM
  • Enzyme Assays: 10-100 μM
  • In Vivo Studies: 0.1-1 mg/kg

5. Industry Case Studies

Case 1: Pharmaceutical company X improved drug metabolite analysis by 40% through optimized CoA supplementation in hepatocyte models.

Case 2: Research institute Y achieved breakthrough in lipid metabolism studies using CoA stabilization techniques.

6. Client Success Stories

Client A: Global biotech firm increased enzyme production yield by 28% through customized CoA protocols.

Client B: University research team published Nature paper on CoA-mediated cancer metabolism mechanisms.

7. Technical Support & Ordering

Contact our biochemistry specialists:

Email: info@vivalr.com
Phone: (86) 15866781826

Request batch-specific COA or discuss custom formulations.

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