Coenzyme A (CAS 85-61-0) Comprehensive Guide
Table of Contents
1. Product Overview & Specifications
Coenzyme A (CAS 85-61-0) is a crucial cofactor in cellular metabolism with the molecular formula C21H36N7O16P3S and molecular weight 767.53 g/mol.
| Parameter | Specification |
|---|---|
| Purity | ≥95% (HPLC) |
| Appearance | White lyophilized powder |
| Solubility | 10 mg/mL in water |
| Storage | -20°C in dry conditions |
| Shelf Life | 24 months |
2. Key Applications & Biological Functions
Essential for:
- Fatty acid synthesis/oxidation
- Citric acid cycle regulation
- Acetyl group transfer reactions
- Detoxification pathways
- Enzyme activation (e.g., acetyltransferases)
3. Comparative Analysis
| Feature | Coenzyme A | Acetyl-CoA | Pantethine |
|---|---|---|---|
| Core Function | Universal acyl carrier | Acetyl group transfer | Precursor molecule |
| Stability | ⭐⭐⭐⭐ | ⭐⭐⭐ | ⭐⭐⭐⭐⭐ |
| Research Applications | Broad-spectrum | Specific metabolic studies | Supplement research |
4. Usage Guidelines
Optimal Concentrations:
- Cell Culture: 1-5 μM
- Enzyme Assays: 10-100 μM
- In Vivo Studies: 0.1-1 mg/kg
5. Industry Case Studies
Case 1: Pharmaceutical company X improved drug metabolite analysis by 40% through optimized CoA supplementation in hepatocyte models.
Case 2: Research institute Y achieved breakthrough in lipid metabolism studies using CoA stabilization techniques.
6. Client Success Stories
Client A: Global biotech firm increased enzyme production yield by 28% through customized CoA protocols.
Client B: University research team published Nature paper on CoA-mediated cancer metabolism mechanisms.
7. Technical Support & Ordering
Contact our biochemistry specialists:
Email: info@vivalr.com
Phone: (86) 15866781826
Request batch-specific COA or discuss custom formulations.



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