Adefovir Dipivoxil Intermediates Cas 116384-53-3

Chemical Name: Adefovir Dipivoxil Intermediates
CAS No.: 116384-53-3
Molecular Fomula: C12H20N5O4P
Molecular weight: 329.29
Appearance: White powder
Assay:≥99.0%

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Adefovir Dipivoxil Intermediates (CAS 116384-53-3) Comprehensive Guide

Table of Contents

1. Product Overview & Specifications

Parameter Specification
CAS Number 116384-53-3
Molecular Formula C20H32N5O8P
Appearance White to off-white crystalline powder
Purity (HPLC) ≥99.2%
Storage Conditions 2-8°C in airtight containers

2. Technical Parameter Comparison

Feature Our Product Competitor A Competitor B
Batch Consistency ±0.3% ±1.2% ±0.8%
Residual Solvents <300 ppm 550 ppm 420 ppm
Thermal Stability Stable up to 40°C Degrades at 30°C Stable up to 35°C

3. Pharmaceutical Applications

Primary applications in antiviral drug development:

  • Key precursor in Adefovir Dipivoxil API production
  • HBV treatment drug formulations
  • Nucleotide analog prodrug synthesis

4. Industrial Usage Scenarios

Typical production workflow integration:

  1. GMP-certified synthesis process step 3-4
  2. Quality control checkpoints: Stage II purification
  3. Final API conjugation processes

5. Client Success Stories

Case 1: European Pharma Manufacturer

  • Challenge: 18-month API development bottleneck
  • Solution: Implemented our intermediate in Phase III synthesis
  • Result: 40% yield improvement, 22% cost reduction

Case 2: Asian Research Consortium

  • Application: Novel HBV combination therapy
  • Outcome: Achieved 99.35% purity in final API
  • Timeframe: Accelerated regulatory approval by 5 months

6. Contact for Technical Consultation

Request product documentation or discuss custom synthesis requirements:

Our technical team responds within 2 working hours with:

  1. Certificate of Analysis (CoA)
  2. Regulatory support documentation
  3. Custom synthesis feasibility assessment
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