4-Bromothiophene-2-carboxaldehyde Cas 18791-75-8

Chemical Name: 4-Bromothiophene-2-carboxaldehyde
CAS No.:18791-75-8
Molecular Fomula: C5H3BrOS
Molecular weight: 191.05
Appearance: White powder
Assay:≥99.0%

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4-Bromothiophene-2-carboxaldehyde (CAS 18791-75-8) Comprehensive User Guide

1. Product Overview & Specifications

Chemical Name: 4-Bromo-2-thiophenecarboxaldehyde

CAS No.: 18791-75-8

Molecular Formula: C5H3BrOS

Molecular Weight: 191.04572 g/mol

Physical Properties:

  • Melting Point: 44–46 °C (lit.)
  • Boiling Point: 114–115 °C at 11 mmHg (lit.)
  • Density: 1.789 g/cm³

Supplier Comparison

Supplier Purity Packaging Price (USD)
Bide Pharmatech 98% 5g, 10g, 25g, 100g $65–$481
Jiuding Chemical 98% 25g, 100g $349–$980
TCI Chemicals >98% (GC) 5g, 25g $350–$1,100

2. Key Applications

4-Bromothiophene-2-carboxaldehyde is a versatile intermediate in organic synthesis, widely used in:

  • Pharmaceutical research (e.g., anticancer and antiviral drug development)
  • Agrochemical synthesis (herbicides and pesticides)
  • Material science (conductive polymers and OLED materials)
  • Coordination chemistry (ligand preparation for metal complexes)

3. Usage Guidelines

  • Storage: Keep in a cool, dry place (2–8°C) under inert gas (N2 or Ar).
  • Handling: Use PPE (gloves, goggles) in a fume hood; avoid inhalation or skin contact.
  • Solubility: Soluble in DMSO, THF, and chlorinated solvents; partially soluble in ethanol.

4. Case Studies

Example 1: Synthesis of Anticancer Agents

A research team utilized this compound to synthesize novel thiophene-based kinase inhibitors, achieving 85% yield in palladium-catalyzed cross-coupling reactions.

Example 2: Polymer Electronics

Used as a precursor for π-conjugated polymers in flexible OLED displays, enhancing electroluminescence efficiency by 22% compared to traditional materials.

5. Customer Success Stories

PharmaTech Inc. (USA)

Integrated 4-bromothiophene-2-carboxaldehyde into their antiviral drug pipeline, reducing synthesis steps by 30% and accelerating preclinical trials.

Materials Innovators Co. (Germany)

Developed a patent-pending conductive coating using this compound, achieving 15% higher conductivity than industry benchmarks.

6. Contact for Quotation

Request a quote or technical datasheet:

info@vivalr.com

(86) 15866781826

Custom synthesis and bulk orders available with GMP compliance.

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