4-Bromothiophene-2-carboxaldehyde (CAS 18791-75-8) Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Chemical Name: 4-Bromo-2-thiophenecarboxaldehyde
CAS No.: 18791-75-8
Molecular Formula: C5H3BrOS
Molecular Weight: 191.04572 g/mol
Physical Properties:
- Melting Point: 44–46 °C (lit.)
- Boiling Point: 114–115 °C at 11 mmHg (lit.)
- Density: 1.789 g/cm³
Supplier Comparison
| Supplier | Purity | Packaging | Price (USD) |
|---|---|---|---|
| Bide Pharmatech | 98% | 5g, 10g, 25g, 100g | $65–$481 |
| Jiuding Chemical | 98% | 25g, 100g | $349–$980 |
| TCI Chemicals | >98% (GC) | 5g, 25g | $350–$1,100 |
2. Key Applications
4-Bromothiophene-2-carboxaldehyde is a versatile intermediate in organic synthesis, widely used in:
- Pharmaceutical research (e.g., anticancer and antiviral drug development)
- Agrochemical synthesis (herbicides and pesticides)
- Material science (conductive polymers and OLED materials)
- Coordination chemistry (ligand preparation for metal complexes)
3. Usage Guidelines
- Storage: Keep in a cool, dry place (2–8°C) under inert gas (N2 or Ar).
- Handling: Use PPE (gloves, goggles) in a fume hood; avoid inhalation or skin contact.
- Solubility: Soluble in DMSO, THF, and chlorinated solvents; partially soluble in ethanol.
4. Case Studies
Example 1: Synthesis of Anticancer Agents
A research team utilized this compound to synthesize novel thiophene-based kinase inhibitors, achieving 85% yield in palladium-catalyzed cross-coupling reactions.
Example 2: Polymer Electronics
Used as a precursor for π-conjugated polymers in flexible OLED displays, enhancing electroluminescence efficiency by 22% compared to traditional materials.
5. Customer Success Stories
PharmaTech Inc. (USA)
Integrated 4-bromothiophene-2-carboxaldehyde into their antiviral drug pipeline, reducing synthesis steps by 30% and accelerating preclinical trials.
Materials Innovators Co. (Germany)
Developed a patent-pending conductive coating using this compound, achieving 15% higher conductivity than industry benchmarks.
6. Contact for Quotation
Request a quote or technical datasheet:
(86) 15866781826
Custom synthesis and bulk orders available with GMP compliance.



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