4-Nitro-N-methylphthalimide CAS 41663-84-7

Chemical Name: 4-Nitro-N-methylphthalimide
CAS No.: 41663-84-7
Appearance: White Powder
Assay:≥ 98%

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4-Nitro-N-methylphthalimide (CAS 41663-84-7) Comprehensive User Guide

1. Product Overview & Specifications

Basic Chemical Properties

CAS Number: 41663-84-7
Molecular Formula: C9H6N2O4
Molecular Weight: 206.16 g/mol
Appearance: Light yellow crystalline powder
Melting Point: 158-162°C
Solubility: Soluble in DMF, DMSO; sparingly soluble in ethanol

Comparative Analysis

Parameter 4-Nitro-N-methylphthalimide N-Methylphthalimide 4-Chloro-N-methylphthalimide
Reactivity High (nitro group) Moderate Moderate-High
Thermal Stability Up to 250°C Up to 220°C Up to 230°C
Pharmaceutical Use API Intermediate Limited Specialty Applications

2. Key Applications & Industrial Uses

Pharmaceutical Intermediates

Widely used in synthesizing:
– Antifungal agents
– Kinase inhibitors
– Neuroprotective compounds

Agrochemical Production

Critical component for:
– Herbicide metabolites
– Insect growth regulators
– Soil treatment additives

Advanced Material Science

Essential for:
– High-performance polymer crosslinkers
– OLED precursor materials
– Specialty coating additives

3. Usage Scenarios & Best Practices

Scenario 1: Antifungal Drug Synthesis

Process Flow:
1. Nitro reduction under H2/Pd-C catalysis
2. Amide formation with triphosgene
3. Purification via recrystallization

Scenario 2: Polymer Modification

Recommended Protocol:
– Use 0.5-2.0% w/w in epoxy systems
– Cure at 120-150°C for optimal crosslinking
– Compatible with BPA-based resins

4. Client Success Stories

Case 1: PharmaTech Innovations

Challenge: Required high-purity intermediate for Phase III clinical trial material
Solution: Custom micronization (D90 < 50μm) with 99.8% HPLC purity
Outcome: Accelerated regulatory approval by 18%

Case 2: AgroShield Solutions

Challenge: Degradation issues in soil-applied herbicides
Solution: Co-formulation with 4-Nitro-N-methylphthalimide stabilizer
Result: Extended field efficacy by 40%

5. Technical Inquiry & Ordering

For technical specifications sheets or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Us?

  • ISO 9001-certified production
  • Batch-to-batch consistency (RSD < 0.5%)
  • Custom particle size distribution options

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