2(5h)-furanone cas 497-23-4

Chemical Name:2(5H)-Furanone
CAS No.: 497-23-4
Molecular Formula:C4H4O2
Molecular Weight:84.07
Appearance:Light yellow liquid

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Table of Contents

1. Product Overview: 2(5H)-Furanone CAS 497-23-4

Technical Specifications

Parameter Value
Chemical Name 2(5H)-Furanone
CAS Number 497-23-4
Molecular Formula C₄H₄O₂
Molecular Weight 84.07 g/mol
Appearance Colorless to pale yellow liquid
Purity ≥98% (GC analysis)
Melting Point -20°C
Boiling Point 85-87°C at 10 mmHg
Solubility Miscible with organic solvents
Storage 2-8°C in airtight container

2. Specifications Comparison

Feature 2(5H)-Furanone γ-Butyrolactone 5-Methyl-2(5H)-furanone
Reactivity High dienophile activity Moderate Low
Pharma Applications Antiviral intermediates Solvent use Limited
Thermal Stability Stable below 40°C High Moderate

3. Key Applications

3.1 Pharmaceutical Intermediates

Used in synthesis of:

  • Antiviral agents (e.g., protease inhibitors)
  • Anticancer drug precursors

3.2 Organic Synthesis

Critical for Diels-Alder reactions in:

  • Chiral compound production
  • Polymer modification

3.3 Flavor & Fragrance

Precursor for:

  • Caramel-like aroma compounds
  • Fruity flavor enhancers

4. Usage Guidelines

Handling Recommendations

  • Use under nitrogen atmosphere
  • Maintain reaction temps <60°C

Reaction Example

Diels-Alder reaction with 1,3-butadiene:

2(5H)-Furanone + 1,3-Butadiene → Bicyclic lactone (95% yield)

5. Client Case Studies

Case 1: ABC Pharma Solutions

Parameter Detail
Application Synthesis of antiviral drug intermediate
Result 20% yield improvement vs traditional methods
Volume 500kg/month contract

Case 2: FlavoTech Inc.

Parameter Detail
Application Production of premium food flavoring
Result 30% cost reduction in flavor synthesis
Certification GRAS approval achieved

6. Contact for Quotation

Request custom pricing and technical support:

  • Email: info@vivalr.com
  • Tel: (86) 15866781826

Our experts will respond within 2 business hours with:

  • MSDS documentation
  • Bulk pricing tiers
  • Custom synthesis options
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