Beta-Sitosterol Cas 83-46-5

Synonyms: alpha-Dihydrofucosterol; 22,23-Dihydrostigmasterol; 24beta-Ethylcholesterol; 5-Stigmasten-3beta-ol; β-Sitosteol
Appearance: White powder
Assay: 40%-99%
Packing: 25kg/fiber drum
Sample: Available

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Beta-Sitosterol (CAS 83-46-5) Comprehensive Product Guide

1. Product Specifications & Comparative Analysis

Parameter Beta-Sitosterol (General) High-Purity Grade (≥95%) Standard Grade (75-90%)
CAS Number 83-46-5
Molecular Formula C29H50O
Molecular Weight 414.71 g/mol
Appearance White crystalline powder
Melting Point 139-142°C
Solubility Ethanol, Chloroform, Ether ≥95% in organic solvents 75-90% with co-solubles
Storage 2-8°C in dry environment

2. Applications & Functional Properties

Core Applications:

  • Pharmaceuticals: Cholesterol-lowering agent, anti-inflammatory formulations
  • Nutraceuticals: Dietary supplements for cardiovascular health
  • Cosmetics: Skin barrier repair in creams and serums
  • Industrial: Stabilizer in biodegradable lubricants

Mechanism of Action:

  • Competitively inhibits intestinal cholesterol absorption
  • Modulates LDL receptor activity
  • Anti-proliferative effects in cellular pathways

3. Usage Guidelines

Recommended Formulations:

  • Oral Tablets: 300-500 mg/day with meals
  • Topical Creams: 0.5-2% w/w in emulsion base
  • Injectable Solutions: Requires lipid-based carriers

Processing Notes:

  • Maintain temperature below 60°C during mixing
  • Use antioxidant agents in oxidative environments

4. Industry Case Studies

Case 1: Cardiovascular Supplement Development

  • Client: European Nutraceutical Manufacturer
  • Application: 400 mg capsules combined with omega-3
  • Outcome: 18% reduction in serum cholesterol (12-week trial)

Case 2: Dermatological Formulation

  • Client: US Cosmetic Brand
  • Application: 1.2% in anti-aging serum
  • Outcome: 34% improvement in skin elasticity metrics

5. Safety & Regulatory Compliance

  • GRAS status (FDA 21 CFR 184.1400)
  • REACH registered (EC 201-480-6)
  • Adverse Effects: Mild GI disturbance at >3g/day

6. Contact for Technical Consultation

Request formulation support or bulk pricing:

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