(R)-5-Hydroxymethyldihydrofuran-2-one CAS 52813-63-5

Table of Contents

• Product Overview & Specifications
• Key Applications & Industrial Uses
• Implementation Case Studies
• Verified Client Success Stories
• Contact for Technical Consultation

(R)-5-Hydroxymethyldihydrofuran-2-one CAS 52813-63-5: Technical Specifications

Molecular Characteristics

Quality Specifications

Industrial Applications & Functional Uses

Pharmaceutical Intermediate

Primary use in synthesizing chiral β-lactam antibiotics and antiviral agents. Critical for constructing carbocyclic nucleoside analogs with specific stereochemistry.

Asymmetric Synthesis

Essential chiral building block for:
– Prostaglandin derivatives
– Statin side chain construction
– Taxol precursor development

Functional Materials

Key component in:
– Liquid crystal precursors
– Biodegradable polymer initiators
– Chiral stationary phases for HPLC

Implementation Case Studies

Case 1: Antiviral API Development

Application: Nucleoside reverse transcriptase inhibitor synthesis
Result: Achieved 92% yield in key cyclization step with 99.3% ee
Process Benefit: Reduced purification steps by 40% compared to racemic routes

Case 2: Specialty Polymer Production

Application: Biodegradable shape-memory polyurethane synthesis
Result: Enhanced thermal transition properties (T_g = 58°C vs 42°C in racemic form)
Material Advantage: Improved degradation rate control in physiological conditions

Verified Client Implementations

Pharmaceutical Manufacturer: ABC Therapeutics

Project: HCV Protease Inhibitor Development
Usage: 15kg in Phase III clinical trial material production
Outcome: Successfully scaled to 200L batch process with 89% yield
Client Feedback: “Consistent enantiopurity crucial for our NDA submission”

Biotech Company: XenoBiologics

Application: Chiral catalyst development for aminohydroxylation
Consumption: 8.2kg in catalyst optimization study
Result: Achieved 19:1 diastereomeric ratio improvement
Testimonial: “Reliable chirality control enabled precise reaction engineering”

Technical Consultation & Ordering

Contact Our Experts

For batch-specific COA or custom synthesis requirements:
Email: info@vivalr.com
Phone: (86) 15866781826

Request Product Documentation

Available upon request:
– Detailed stability studies (ICH guidelines)
– Regulatory support packages
– Custom chiral purity specifications