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N-Boc-trans-4-Hydroxy-L-proline Methyl Ester (CAS 74844-91-0) Ultimate Guide
Table of Contents
- Product Specifications & Comparative Analysis
- Detailed Applications in Pharmaceutical Research
- Operational Protocols & Best Practices
- Industry Implementation Case Studies
- Verified Client Success Stories
- Expert Consultation & Quotation Request
Product Specifications & Comparative Analysis
| Parameter | Specification | Competitor A | Competitor B |
|---|---|---|---|
| Chemical Name | N-Boc-trans-4-Hydroxy-L-proline Methyl Ester | Alternative naming conventions | Varied protective groups |
| CAS Number | 74844-91-0 | Different CAS | Different CAS |
| Molecular Formula | C12H19NO5 | Similar structure | Different ester groups |
| Purity | ≥98.5% (HPLC) | 95-97% | 98% |
| Storage | 2-8°C desiccated | Room temperature | Refrigerated |
Detailed Applications in Pharmaceutical Research
Key Functional Applications:
- Peptide synthesis backbone modification
- Protease inhibitor development
- Chiral auxiliary in asymmetric synthesis
- GPCR-targeted drug intermediates
- Bioconjugation techniques
Operational Protocols & Best Practices
Recommended Implementation Workflow:
- Storage: Maintain nitrogen atmosphere
- Handling: Use anhydrous conditions
- Reaction: Optimize at 0.1M concentration
- Purification: Reverse-phase HPLC
- QC: NMR and mass spec verification
Industry Implementation Case Studies
Case 1: Antiviral Drug Development
Used as key intermediate in HCV protease inhibitor synthesis…
Case 2: Oncology Research Application
Critical component in PARP inhibitor scaffold construction…
Verified Client Success Stories
PharmaTech Solutions (USA)
“Achieved 92% yield improvement in our lead compound synthesis…”
BioSynthexis GmbH (Germany)
“Reduced chiral purification steps from 5 to 2 in API production…”
Expert Consultation & Quotation Request
Contact our technical team:
Email: info@vivalr.com
Tel: (86) 15866781826
Request custom synthesis scale-up protocols or bulk pricing:
- Current lead time: 3-5 business days
- MOQ: 100mg lab scale
- GMP-grade available
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