3-Chloropropyl Isocyanate Cas 13010-19-0

Chemical Name: 3-Chloropropyl isocyanate
CAS No.: 13010-19-0
Molecular Fomula: C4H6ClNO
Molecular weight: 119.55
Appearance: Transparent colorless liquid
Assay:99%

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Table of Contents

1. Product Overview & Specifications

3-Chloropropyl Isocyanate (CAS 13010-19-0)

Parameter Specification Competitor A Competitor B
Molecular Formula C4H4ClNO C4H4ClNO C4H4ClNO
Purity ≥98% ≥95% ≥97%
Boiling Point 72-74°C (15 mmHg) 70-75°C 73-75°C
Storage Conditions 2-8°C in dark Ambient 0-5°C

2. Key Applications & Industrial Uses

Pharmaceutical Intermediates

Widely used in synthesizing β-blockers and antipsychotic drugs requiring chloroalkyl functional groups.

Agrochemical Production

Critical component in creating chlorinated urea herbicides with enhanced leaf penetration efficiency.

Polymer Modification

Enables introduction of isocyanate groups into silicone resins for improved thermal stability (up to 300°C).

3. Usage Guidelines & Safety Protocols

Handling Requirements

  • Use PPM-controlled environments below 0.1% concentration
  • Maintain nitrogen atmosphere during transfer operations

Reaction Optimization

Application Recommended Solvent Temperature Range
Urea Synthesis Dry THF -10°C to 5°C
Polymer Functionalization Anhydrous DCM 20-25°C

4. Industry Case Studies

Case 1: Cardiovascular Drug Intermediate

Client: Top 10 Global Pharma Company
Challenge: Achieve 99.5% purity for GMP-grade intermediate
Solution: Optimized distillation parameters (72°C @ 12 mmHg)
Result: 99.7% purity with 92% yield

Case 2: High-Performance Silicone Sealant

Client: Specialty Materials Manufacturer
Challenge: Improve adhesive strength under 250°C
Solution: 3-stage functionalization process
Result: 40% increase in thermal resistance

5. Request Customized Solutions

Contact our technical team for application-specific support:

Email: info@vivalr.com
Phone: (86) 15866781826

24-hour response guarantee: Submit your synthesis challenges before 3PM CST for same-day formulation advice.

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