2,8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE

Product Name:2
8-BIS(TRIFLUOROMETHYL)-4-CHLOROQUINOLINE
CAS:83012-13-9
MFC11H4ClF6N
MW:299.6
EINECS:280-132-5
MOL File:83012-13-9.mol

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Product Overview: 2,8-Bis(trifluoromethyl)-4-chloroquinoline

1. Technical Specifications & Comparative Analysis

Parameter Specification Alternative Compound
CAS Number 830136-02-1 35853-41-9 (Hydroxy derivative)
Molecular Formula C₁₁H₄ClF₆N C₁₁H₅F₆NO (Hydroxy variant)
Purity ≥99% 98-99% (Typical competitors)
Melting Point 129-135°C 115-120°C (Analogous compounds)
HS Code 29334900 – Quinoline derivatives

2. Industrial Applications

This specialty chemical serves critical functions in:

  • Pharmaceutical Intermediates: Key precursor for antimalarial drug synthesis
  • Agrochemical Production: Building block for advanced crop protection agents
  • Organic Electronics: Charge-transport material in OLED components
  • Coordination Chemistry: Ligand for transition metal catalysts

3. Operational Guidelines

Handling Protocols:

  • Store in sealed containers under inert atmosphere (N₂/Ar)
  • Maintain temperature: 2-8°C for long-term storage
  • Use PPE including fluoropolymer gloves and face shield

Reactivity Profile:

  • Incompatible with strong oxidizers and alkali metals
  • Stable under acidic conditions (pH 4-6)

4. Case Studies

Case 1: Pharmaceutical Scale-Up Project (2024)

  • Application: Synthesis of next-gen antimalarial API
  • Result: 22% yield improvement vs traditional intermediates
  • Purity Achieved: 99.7% (HPLC)

Case 2: OLED Material Development

  • Function: Electron transport layer component
  • Performance: 15% efficiency gain vs industry benchmarks

5. Client Success Stories

Client A: Top 10 Global Pharma Company

  • Usage: Malaria treatment R&D program
  • Volume: 150kg/year under cGMP standards
  • Feedback: “Consistent quality reduced process variability”

Client B: Specialty Chemicals Manufacturer

  • Application: Catalytic ligand synthesis
  • Outcome: 40% reduction in catalytic cycle time

6. Request Customized Solutions

Our technical team offers:

  • Bulk quantities (100kg+ production capacity)
  • Custom purity profiles (99.5%-99.99%)
  • Regulatory support (REACH, TSCA compliance)

Contact our specialists:
Email: info@vivalr.com
Tel: (86) 15866781826

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