Product Overview: 2,8-Bis(trifluoromethyl)-4-chloroquinoline
Table of Contents
1. Technical Specifications & Comparative Analysis
| Parameter | Specification | Alternative Compound |
|---|---|---|
| CAS Number | 830136-02-1 | 35853-41-9 (Hydroxy derivative) |
| Molecular Formula | C₁₁H₄ClF₆N | C₁₁H₅F₆NO (Hydroxy variant) |
| Purity | ≥99% | 98-99% (Typical competitors) |
| Melting Point | 129-135°C | 115-120°C (Analogous compounds) |
| HS Code | 29334900 – Quinoline derivatives | |
2. Industrial Applications
This specialty chemical serves critical functions in:
- Pharmaceutical Intermediates: Key precursor for antimalarial drug synthesis
- Agrochemical Production: Building block for advanced crop protection agents
- Organic Electronics: Charge-transport material in OLED components
- Coordination Chemistry: Ligand for transition metal catalysts
3. Operational Guidelines
Handling Protocols:
- Store in sealed containers under inert atmosphere (N₂/Ar)
- Maintain temperature: 2-8°C for long-term storage
- Use PPE including fluoropolymer gloves and face shield
Reactivity Profile:
- Incompatible with strong oxidizers and alkali metals
- Stable under acidic conditions (pH 4-6)
4. Case Studies
Case 1: Pharmaceutical Scale-Up Project (2024)
- Application: Synthesis of next-gen antimalarial API
- Result: 22% yield improvement vs traditional intermediates
- Purity Achieved: 99.7% (HPLC)
Case 2: OLED Material Development
- Function: Electron transport layer component
- Performance: 15% efficiency gain vs industry benchmarks
5. Client Success Stories
Client A: Top 10 Global Pharma Company
- Usage: Malaria treatment R&D program
- Volume: 150kg/year under cGMP standards
- Feedback: “Consistent quality reduced process variability”
Client B: Specialty Chemicals Manufacturer
- Application: Catalytic ligand synthesis
- Outcome: 40% reduction in catalytic cycle time
6. Request Customized Solutions
Our technical team offers:
- Bulk quantities (100kg+ production capacity)
- Custom purity profiles (99.5%-99.99%)
- Regulatory support (REACH, TSCA compliance)
Contact our specialists:
Email: info@vivalr.com
Tel: (86) 15866781826


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