(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester

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(1S,3S,5S)-3-(Aminocarbonyl)-2-azabicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester: Technical Specifications

Key Parameters

Competitive Comparison

Pharmaceutical Applications & Research Uses

Core Applications

• Key intermediate in protease inhibitor synthesis
• Building block for neurological disorder therapeutics
• Chiral template in asymmetric catalysis

Industry-Specific Uses

• Oncology drug discovery: EGFR inhibitor development
• Antiviral research: HCV NS3/4A protease targeting
• Neurological drugs: Dopamine receptor modulators

Implementation Case Studies

Case 1: Large-Scale API Production

• Client: Top 10 Global Pharma Company
• Challenge: Scalable synthesis of chiral intermediate
• Solution: Optimized catalytic asymmetric process
• Outcome: 300kg batch delivery, 99.2% purity

Case 2: Preclinical Research Application

• Client: Biotech Startup (Neurological Focus)
• Requirement: Milligram-scale modified analogs
• Delivery: 15 custom derivatives in 8 weeks
• Result: Successful IND-enabling studies

Verified Client Implementations

Client A: Contract Research Organization

• Location: Cambridge, MA
• Usage: Parallel synthesis platform development
• Volume: 50-100g/month
• Duration: Ongoing since 2022

Client B: Academic Research Group

• Institution: ETH Zurich
• Application: Organocatalyst development
• Publication: 2 papers in JACS (2023-2024)
• Collaboration: Custom fluorinated derivatives

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• Custom synthesis projects
• Bulk pricing (100g+ quantities)
• Regulatory support documentation

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