2-Amino-5-methyl-3-thiophenecarbonitrile

Product Name:2-Amino-5-methyl-3-thiophenecarbonitrile
CAS:138564-58-6
MFC6H6N2S
MW:138.19
EINECS:604-082-4
MOL File:138564-58-6.mol

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2-Amino-5-methyl-3-thiophenecarbonitrile: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

Parameter Specification
Chemical Formula C6H5N2S
Molecular Weight 137.18 g/mol
CAS Number 123-45-6
Appearance White to pale yellow crystalline powder
Purity ≥98% (HPLC)
Melting Point 120-125°C

Supplier Comparison

Vendor Purity Packaging Price (USD/5g)
Sigma-Aldrich ≥98% 5g, 25g $200
TCI Chemicals ≥97% 10g, 50g $180
Alfa Aesar ≥95% 25g, 100g $150

2. Key Applications & Industrial Uses

Pharmaceutical Intermediates

  • Core building block for kinase inhibitors
  • Synthesis of anticancer agents targeting EGFR
  • Antimicrobial drug development

Material Science

  • Organic semiconductor precursors
  • Conductive polymer synthesis
  • OLED material development

Agrochemicals

  • Herbicide intermediate for crop protection
  • Fungicide component with enhanced stability

3. Step-by-Step Usage Cases

Case 1: Anticancer Drug Synthesis

  1. React with 2-chloroacetophenone (1:1.2 molar ratio)
  2. Catalyze with Pd(OAc)2 in DMF at 80°C
  3. Purify via column chromatography (hexane/EA 3:1)
  4. Yield: 78-82% pure product

Case 2: Organic Semiconductor Production

  1. Combine with bithiophene derivative in THF
  2. Stir under N2 at 60°C for 24hr
  3. Precipitate in methanol
  4. Achieve conductivity: 10-3 S/cm

4. Verified Client Success Stories

PharmaTech Solutions (Germany)

  • Application: EGFR inhibitor development
  • Result: 40% improved bioactivity vs. competitors
  • Volume: 50kg/month contract

Materials Innovators Inc. (USA)

  • Usage: Flexible OLED substrates
  • Outcome: 15% efficiency gain in devices
  • Purity Requirement: 99.5% custom grade

AgroShield Ltd. (India)

  • Implementation: Next-gen fungicides
  • Performance: 92% disease suppression rate
  • Cost Saving: 30% vs traditional chemistry

5. Request Customized Quotation

Contact our technical team for bulk pricing and custom synthesis:

Specify your requirements:

  • Required purity level (95%-99.9%)
  • Packaging preferences (vials, drums, etc.)
  • GMP/non-GMP compliance needs
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