7-FLUORO-2-METHYLQUINOLINE: Product Guide & User Insights
Table of Contents
- Product Overview & Specifications
- Applications & Industry Use Cases
- Technical Comparisons
- Safety & Handling Guidelines
- Client Case Studies
- Request a Quote or Sample
Product Overview & Specifications
7-Fluoro-2-methylquinoline (CAS 91498-52-3) is a fluorinated quinoline derivative with a molecular formula C10H8FN. Key parameters:
| Parameter | Value |
|---|---|
| Purity | ≥98% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Melting Point | 112–116°C |
| Solubility | Soluble in DMSO, methanol; sparingly in water |
| Storage | 2–8°C in airtight container |
Applications & Industry Use Cases
Widely used in:
- Pharmaceutical Intermediates: Key building block for antitumor and antiviral drugs.
- Agrochemicals: Synthesis of fluorinated pesticides with enhanced bioavailability.
- Material Science: Fluorophore in OLEDs due to its stable fluorescence.
- Research Reagents: Ligand in catalytic reactions (e.g., Suzuki-Miyaura coupling).
Technical Comparisons
| Feature | 7-Fluoro-2-methylquinoline | 2-Methylquinoline | 6-Fluoroquinoline |
|---|---|---|---|
| Fluorine Position | C7 | N/A | C6 |
| Reactivity | High (directs electrophiles to C5/C8) | Moderate | Moderate |
| Bioactivity | Enhanced membrane permeability | Standard | Intermediate |
Safety & Handling Guidelines
- Wear PPE (gloves, goggles) to prevent skin/eye contact.
- Store away from light/moisture; shelf life: 24 months unopened.
- Dispose via certified chemical waste channels.
Client Case Studies
Case 1: Anticancer Drug Development
A European pharma company used 7-Fluoro-2-methylquinoline to synthesize FGFR inhibitors, achieving 92% yield in Buchwald-Hartwig amination.
Case 2: OLED Material Optimization
A Japanese electronics firm incorporated the compound into blue-emitting layers, improving device efficiency by 18% vs. non-fluorinated analogs.
Request a Quote or Sample
Contact us for:
- Bulk pricing (1kg to ton-scale)
- Custom synthesis (purity 95–99.9%)
- Technical documentation (CoA, MSDS)
Email: info@vivalr.com
Phone: (86) 15866781826
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