5-Fluoro-2-oxindole

5-Fluoro-2-oxindole Comprehensive Product Guide

Table of Contents

• Product Overview
• Specifications & Comparative Analysis
• Detailed Applications
• Usage Case Studies
• Client Success Stories
• Request a Quote

Product Overview

5-Fluoro-2-oxindole (CAS: 56341-41-4) is a fluorinated heterocyclic compound widely used in pharmaceutical synthesis. Key identifiers:

• Molecular Formula: C₈H₆FNO
• Molecular Weight: 151.13 g/mol
• Appearance: Pale yellow crystalline solid
• Melting Point: 143–147°C
• Boiling Point: 307.2°C at 760 mmHg
• Safety: Xi (Irritant), C (Corrosive); R36/37/38

Specifications & Comparative Analysis

Detailed Applications

Primary industrial and research uses include:

• Pharmaceutical Intermediate: Key precursor in Sunitinib (anticancer drug) synthesis.
• Antibacterial Research: Structural backbone for quinolone derivatives with in vitro activity.
• Organic Synthesis: Building block for fluorinated indole derivatives.

Usage Case Studies

Case 1: Anticancer Drug Development
A research team utilized 5-Fluoro-2-oxindole to optimize Sunitinib’s synthesis, achieving 92% yield under modified catalytic conditions.

Case 2: Antibacterial Agent Design
Incorporated into 1-(5-fluoro-2-pyridyl)quinolone derivatives, demonstrating MIC values of ≤2 μg/mL against Gram-positive pathogens.

Client Success Stories

Client A: PharmaCorp Inc.
Scaled production of 5-Fluoro-2-oxindole to 500 kg/month, reducing synthesis costs by 18% via proprietary purification methods.

Client B: BioResearch Ltd.
Developed a novel fluorinated kinase inhibitor using this compound, advancing to Phase II clinical trials in 2024.

Request a Quote

Contact our team for technical specifications, bulk pricing, or custom synthesis inquiries:

• Email: info@vivalr.com
• Phone: (86) 15866781826