6,7-Dimethoxy-3,4-dihydroquinazoline-4-one: Technical Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Value |
|---|---|
| CAS Number | 13794-72-4 |
| Molecular Formula | C10H10N2O3 |
| Appearance | White to off-white crystalline powder |
| Boiling Point | 374.1 °C at 760 mmHg |
| Density | 1.33 g/cm³ |
| Refractive Index | 1.601 |
2. Key Applications
This compound serves as a critical intermediate in pharmaceutical synthesis, particularly in the production of gefitinib, a tyrosine kinase inhibitor used in cancer therapy. Its structural properties enable:
- Precision in API (Active Pharmaceutical Ingredient) manufacturing
- High-purity synthesis of quinazoline derivatives
- Development of targeted oncology medications
3. Usage Scenarios
Pharmaceutical Synthesis
Used under controlled conditions (GMP standards) for:
- Multi-step organic reactions requiring methoxy-group stability
- Catalytic hydrogenation processes
- Purification via recrystallization (ethanol/water systems)
4. Client Case Studies
Case 1: Oncology Drug Development
Client: Beijing Lingbao Technology Co., Ltd.
Application: Synthesis of gefitinib impurities and intermediates
Outcome: Achieved 99.8% purity in final API batches, complying with ICH Q3A/B guidelines.
Case 2: Research Institute Collaboration
Client: Confidential (Major European Pharma)
Application: Development of novel kinase inhibitors
Outcome: Accelerated lead optimization phase by 40% through improved synthetic routes.
5. Contact for Technical Support
For analytical certificates, bulk pricing, or custom synthesis requirements:
| Email: | info@vivalr.com |
| Phone: | (86) 15866781826 |


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