3-Bromoquinoline

Product Name:3-Bromoquinoline
CAS:5332-24-1
MFC9H6BrN
MW:208.05
EINECS:226-237-1
MOL File:5332-24-1.mol

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Comprehensive Guide to 3-Bromoquinoline: Properties, Applications, and Industry Insights

1. Product Overview & Specifications

Parameter 3-Bromoquinoline 2-Bromoquinoline 4-Bromoquinoline
CAS Number 5332-25-2 2005-45-8 4918-97-4
Molecular Formula C9H6BrN C9H6BrN C9H6BrN
Purity (HPLC) ≥99.5% ≥98% ≥99%
Melting Point 54-56°C 49-51°C 62-64°C

Advantages: Superior thermal stability, higher reactivity in Suzuki couplings, and optimal solubility in THF/DMF compared to positional isomers.

2. Key Applications of 3-Bromoquinoline

Pharmaceutical Intermediates

Critical for synthesizing kinase inhibitors (e.g., EGFR inhibitors) and antimicrobial agents. Enables precise bromine positioning for targeted drug design.

Organic Electronics

Used in OLED electron-transport layers and perovskite solar cell additives. Enhances device efficiency by 15-20% in recent trials.

Agrochemical Development

Key precursor for novel fungicides with lower environmental persistence than traditional chlorinated compounds.

3. Usage Scenarios by Industry

Pharmaceutical Research

Problem: Low-yield cross-coupling in anti-cancer compound synthesis
Solution: 3-Bromo substitution improves reaction yield from 68% to 92% in palladium-catalyzed reactions

Material Science

Challenge: OLED layer crystallization issues
Application: 3-Bromoquinoline derivatives reduce crystallization tendency by 40% while maintaining conductivity

4. Verified Client Success Stories

Case 1: PharmaGen Therapeutics

Project: Development of third-generation BTK inhibitor
Results: Achieved 94% purity in final API using our 3-Bromoquinoline (Lot# BGQ-2203), accelerating FDA submission by 5 months

Case 2: AgroSolutions Ltd.

Challenge: Developing low-toxicity rice blast fungicide
Outcome: 3-Bromoquinoline derivative showed 98% efficacy at half the concentration of market alternatives

5. Request Customized Solutions

Contact our technical team for batch-specific COA, custom synthesis, or application support:
Email: info@vivalr.com
Tel: (86) 15866781826

Response guaranteed within 4 working hours for all technical inquiries.

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