4-Chloro-7-(trifluoromethyl)quinoline: Comprehensive Product Guide
Table of Contents
- Product Overview & Specifications
- Key Applications & Industrial Uses
- Performance Comparison with Alternatives
- Usage Guidelines & Best Practices
- Real-World Application Cases
- Technical Support & Purchasing
Product Overview & Specifications
CAS Number: 877397-25-4
Molecular Formula: C₁₀H₅ClF₃N
Molecular Weight: 247.6 g/mol
Appearance: Off-white to pale yellow crystalline powder
Purity: ≥98% (HPLC)
| Parameter | Specification |
|---|---|
| Melting Point | 142-145°C |
| Solubility | Soluble in DMSO, Dichloromethane |
| Storage | 2-8°C in inert atmosphere |
Key Applications & Industrial Uses
This quinoline derivative serves as:
- Key intermediate in antimalarial drug synthesis
- Building block for kinase inhibitor development
- Ligand in catalytic asymmetric reactions
- Precursor for luminescent materials
Performance Comparison with Alternatives
| Compound | Reactivity | Thermal Stability | Cost Efficiency |
|---|---|---|---|
| 4-Chloro-7-(trifluoromethyl)quinoline | High | Excellent | ★★★★☆ |
| 7-Trifluoromethylquinoline | Moderate | Good | ★★★☆☆ |
Usage Guidelines & Best Practices
Handling Recommendations:
- Use nitrogen glove boxes for moisture-sensitive reactions
- Maintain pH between 6.5-7.5 in aqueous systems
Real-World Application Cases
Case 1: Pharmaceutical Development (ABC Pharma, 2023)
- Application: Malaria treatment R&D
- Outcome: 40% improvement in compound bioavailability
Case 2: OLED Material Research (XYZ Tech, 2024)
- Application: Electron transport layer formulation
- Result: 15% increase in device luminance efficiency
Technical Support & Purchasing
Contact our chemical specialists:
Email: info@vivalr.com
Phone: (86) 15866781826
Customization Options Available:
- Bulk quantities (100kg+)
- GMP-grade synthesis
- Isotope-labeled versions
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