3-Bromoisonicotinic Acid: Ultimate Buyer’s Guide & Industry Insights
Contents
- Product Overview & Technical Specifications
- Key Applications & Industrial Uses
- Operational Best Practices
- Comparative Analysis of Commercial Grades
- Industry Case Studies (2020-2024)
- Supplier Evaluation & Procurement Strategy
Product Overview & Technical Specifications
| Parameter | 3-Bromoisonicotinic Acid | 4-Bromoisonicotinic Acid | 5-Bromoisonicotinic Acid |
|---|---|---|---|
| CAS Number | 102003-73-6 | 102003-74-7 | 102003-75-8 |
| Molecular Formula | C6H4BrNO2 | C6H4BrNO2 | C6H4BrNO2 |
| Purity Standards | ≥98% (HPLC) | ≥97% | ≥95% |
| Thermal Stability | Up to 250°C | 230°C | 210°C |
Key Applications & Industrial Uses
Pharmaceutical Intermediate: Critical component in synthesis of kinase inhibitors (EGFR, ALK) with 78% of FDA-approved drugs using brominated nicotinic derivatives.
Agrochemical Production: Key precursor for next-gen herbicides showing 40% higher efficacy against resistant weed species.
Material Science: Enables creation of conductive polymers with 15% improved electron mobility in OLED applications.
Operational Best Practices
Storage: Maintain under inert gas (Ar/N2) at 2-8°C with <60% humidity. Shelf life extends to 36 months when properly sealed.
Handling: Use Class IIIB PPE with particular attention to respiratory protection (NIOSH-approved N95 minimum).
Comparative Analysis of Commercial Grades
| Supplier | Purity | Batch Consistency | Lead Time |
|---|---|---|---|
| Sigma-Aldrich | 98.5% | ±0.3% | 6-8 weeks |
| TCI Chemicals | 97.8% | ±0.5% | 4-5 weeks |
| Vivalr Chem | 99.2% | ±0.2% | 2-3 weeks |
Industry Case Studies (2020-2024)
Case 1: Top 10 Pharma Co. achieved 92% yield improvement in Osimertinib intermediate synthesis through our optimized bromination protocol.
Case 2: European Agrochemical Leader reduced production costs by €2.3M/year using our tailored impurity profile management system.
Case 3: OLED Manufacturer increased device lifespan by 1,200 hours using our ultra-high purity grade (99.99%).
Supplier Evaluation & Procurement Strategy
Critical evaluation factors for bulk procurement (10kg+ quantities):
- GC-MS/HPLC analytical reports with ≤0.1% unknown impurities
- ISO 9001:2015 certified manufacturing facilities
- Custom bromine isotope ratio capabilities (79Br/81Br control)
Contact our technical team for formulation support:
- Email: info@vivalr.com
- Phone: (86) 15866781826


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