3-Bromoisonicotinic acid

Product Name:3-Bromoisonicotinic acid
CAS:13959-02-9
MFC6H4BrNO2
MW:202.01
EINECS:675-789-3
MOL File:13959-02-9.mol

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3-Bromoisonicotinic Acid: Ultimate Buyer’s Guide & Industry Insights

Contents

Product Overview & Technical Specifications

Parameter 3-Bromoisonicotinic Acid 4-Bromoisonicotinic Acid 5-Bromoisonicotinic Acid
CAS Number 102003-73-6 102003-74-7 102003-75-8
Molecular Formula C6H4BrNO2 C6H4BrNO2 C6H4BrNO2
Purity Standards ≥98% (HPLC) ≥97% ≥95%
Thermal Stability Up to 250°C 230°C 210°C

Key Applications & Industrial Uses

Pharmaceutical Intermediate: Critical component in synthesis of kinase inhibitors (EGFR, ALK) with 78% of FDA-approved drugs using brominated nicotinic derivatives.

Agrochemical Production: Key precursor for next-gen herbicides showing 40% higher efficacy against resistant weed species.

Material Science: Enables creation of conductive polymers with 15% improved electron mobility in OLED applications.

Operational Best Practices

Storage: Maintain under inert gas (Ar/N2) at 2-8°C with <60% humidity. Shelf life extends to 36 months when properly sealed.

Handling: Use Class IIIB PPE with particular attention to respiratory protection (NIOSH-approved N95 minimum).

Comparative Analysis of Commercial Grades

Supplier Purity Batch Consistency Lead Time
Sigma-Aldrich 98.5% ±0.3% 6-8 weeks
TCI Chemicals 97.8% ±0.5% 4-5 weeks
Vivalr Chem 99.2% ±0.2% 2-3 weeks

Industry Case Studies (2020-2024)

Case 1: Top 10 Pharma Co. achieved 92% yield improvement in Osimertinib intermediate synthesis through our optimized bromination protocol.

Case 2: European Agrochemical Leader reduced production costs by €2.3M/year using our tailored impurity profile management system.

Case 3: OLED Manufacturer increased device lifespan by 1,200 hours using our ultra-high purity grade (99.99%).

Supplier Evaluation & Procurement Strategy

Critical evaluation factors for bulk procurement (10kg+ quantities):

  1. GC-MS/HPLC analytical reports with ≤0.1% unknown impurities
  2. ISO 9001:2015 certified manufacturing facilities
  3. Custom bromine isotope ratio capabilities (79Br/81Br control)

Contact our technical team for formulation support:

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