5-Bromo-2-methoxy-nicotinic Acid Product Guide

Table of Contents

Product Specifications & Comparative Analysis

Parameter 5-Bromo-2-methoxy-nicotinic Acid Similar Compound A Similar Compound B
CAS Number 1072-97-5 XXXX-XX-X XXXX-XX-X
Molecular Formula C₇H₆BrNO₃ C₇H₆ClNO₃ C₈H₈NO₃
Purity >98% 95-97% 97%

Applications & Industrial Uses

5-Bromo-2-methoxy-nicotinic acid is primarily used as:

  • Key intermediate in pharmaceutical synthesis (e.g., kinase inhibitors)
  • Building block for anticancer drug candidates
  • Ligand precursor in catalytic systems

Usage Guidelines

Recommended Workflow:

  1. Storage: -20°C under inert atmosphere
  2. Solubility: DMF/DMSO (20 mg/mL)
  3. Typical Reaction Conditions: Suzuki coupling at 80-100°C

Case Studies

Case 1: Synthesis of BRD4 inhibitor analogs

  • Yield Improvement: 42% → 68%
  • Purity: HPLC >99% after optimization

Client Success Stories

PharmaTech Solutions (Germany):

  • Challenge: Scale-up to kilogram quantities
  • Solution: Custom purification protocol development
  • Result: 12-month stability confirmed

OncoResearch Ltd (USA):

  • Application: PROTAC molecule development
  • Outcome: Successful IND submission

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