6-Bromo-2-Chloro-Quinoline: Technical Overview and Application Guide
Table of Contents
1. Chemical Specifications & Comparative Analysis
| Parameter | 6-Bromo-2-Chloro-Quinoline | Analogous Compounds |
|---|---|---|
| CAS Number | 948290-77-5 | 5332-25-2 (6-Bromoquinoline) |
| Molecular Formula | C10H6NCl2Br | C9H6BrN |
| Molecular Weight | 290.97 g/mol | 208.05 g/mol |
| Structural Features | Chloromethyl substitution at position 3 | No chlorine substituents |
2. Functional Applications
This halogenated quinoline derivative demonstrates critical utility in:
- Pharmaceutical intermediate synthesis
- Organic light-emitting diode (OLED) material development
- Coordination chemistry research
- Antimicrobial agent prototypes
Safety Classification: Acute Oral Toxicity Category 3, Severe Eye Damage Category 1 (GHS)
3. Operational Guidelines
Handling Protocols
- Mandatory PPE: Chemical goggles, nitrile gloves
- Engineering controls: Fume hood operation required
- Prohibited actions: No ingestion/exposure during handling
Emergency Procedures
| Exposure Route | First Aid Measures |
|---|---|
| Ocular | Immediate 15-minute flush with saline solution |
| Dermal | Remove contaminated clothing, wash with soap/water |
| Ingestion | Activate medical emergency protocols (DO NOT induce vomiting) |
4. Implementation Case Studies
Case 1: Antimalarial Drug Intermediate
Application: Key precursor in chloroquine analog synthesis
Outcome: Achieved 92% reaction yield in optimized conditions
Case 2: OLED Electron Transport Layer
Application: Charge transport material development
Performance: Enhanced device efficiency by 18% vs. standard materials
5. Client Success Stories
Shanghai Medichem Research Institute
Project: High-throughput screening of quinoline derivatives
Result: Identified 3 lead compounds with antimicrobial activity
Guangzhou Material Science Co., Ltd
Application: Development of corrosion inhibitors
Achievement: 75% reduction in metal degradation rates
6. Technical Consultation
For material specifications sheets or custom synthesis inquiries:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Request MSDS documentation or discuss bulk order requirements with our chemistry specialists.
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