4-Methylquinoline (Lepidine) Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | 4-Methylquinoline | Comparable Compounds |
|---|---|---|
| CAS Number | 491-35-0 | N/A |
| Molecular Formula | C10H9N | C9H7N (Quinoline) |
| Appearance | Colorless oily liquid (turns reddish-brown under light) | Varies by derivative |
| Melting Point | 9°C | -15°C (Quinoline) |
| Boiling Point | 261-263°C | 237°C (Quinoline) |
| Flash Point | 151°C | 99°C (Isoquinoline) |
| Solubility | Soluble in ethanol, ether, acetone; slightly soluble in water | Similar solvent profile |
2. Key Applications & Industrial Uses
Core Functional Roles:
- Pharmaceutical Intermediate: Key precursor for antimalarial agents and antimicrobial compounds
- Dye Manufacturing: Essential component in synthesizing complex heterocyclic dyes
- Coordination Chemistry: Ligand in catalytic metal complexes
- Advanced Materials: Building block for photoactive compounds in OLED development
3. Operational Guidelines & Safety Protocols
Material Handling Requirements:
- Personal Protection: Chemical-resistant gloves (Butyl rubber), ANSI-approved goggles, vapor respirators
- Ventilation: Mandatory fume hood use for open handling
- Containment: Secondary containment vessels required for bulk storage
Emergency Response Matrix:
| Exposure Type | First Response | Medical Follow-up |
|---|---|---|
| Dermal Contact | Flush with water ≥15 mins using safety shower | Dermatological evaluation for persistent irritation |
| Ocular Exposure | Immediate irrigation with eyewash ≥20 mins | Ophthalmologic examination within 2 hrs |
| Inhalation | Evacuate to fresh air, administer oxygen if needed | Pulmonary function monitoring |
4. Industry Application Cases
Case Study 1: Antimalarial Drug Development
Used as primary intermediate in chloroquine analogue synthesis, demonstrating 92% reaction efficiency in GMP production.
Case Study 2: Specialty Dye Synthesis
Critical component in manufacturing lightfast textile dyes, achieving superior color retention in accelerated weathering tests.
5. Client Success Stories
Pharmaceutical Innovator (Germany):
Integrated 4-methylquinoline into novel antimicrobial API synthesis, reducing production costs by 18% while meeting EP 11.0 standards.
Advanced Materials Leader (USA):
Utilized compound as electron-transport layer precursor in flexible OLED displays, achieving 15% efficiency improvement.
6. Technical Consultation & Ordering
Contact our chemical engineering specialists for:
- Custom synthesis solutions
- Bulk order optimization (≥100kg quantities)
- Regulatory compliance support
Email: info@vivalr.com
Tel: (86) 15866781826
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