2-Methoxy-5-nitropyridine: Technical Guide & Applications
Table of Contents
1. Product Overview & Specifications
| Parameter | 2-Methoxy-5-nitropyridine | Comparable Compounds |
|---|---|---|
| CAS Number | 5446-92-4 | 127356-38-1 (4-amino variant) |
| Molecular Formula | C6H6N2O3 | C7H7NO4 (phenolic analog) |
| Appearance | Off-white crystalline powder | Varies by derivative |
| Storage | 2-8°C, dry, inert atmosphere | Similar requirements |
| Key Differentiator | Pyridine core structure | Benzene/phenol derivatives |
2. Key Applications
This specialty chemical serves critical roles in:
- Pharmaceutical intermediates for API synthesis
- Agrochemical research & development
- Ligand design in coordination chemistry
- Building block for nitroaromatic compounds
- Functional material development
3. Usage Guidelines
Handling Protocols
- Use PPE: nitrile gloves, safety goggles
- Process under nitrogen atmosphere
- Limit exposure to moisture
Reaction Compatibility
- Stable in polar aprotic solvents (DMF, DMSO)
- Reactive toward nucleophilic substitution
- Catalytic hydrogenation requires controlled conditions
4. Case Studies
Antimicrobial Agent Development
Used as key precursor in novel quinolone antibiotics synthesis, achieving 92% intermediate yield.
Electronic Materials
Enabled creation of nitro-functionalized conductive polymers with enhanced electron mobility.
5. Client Success Stories
Pharma Innovators Ltd. (Shanghai)
- Application: Anticancer drug intermediate
- Outcome: Reduced synthesis steps from 7 to 4
- Purity Achieved: 99.7% (HPLC)
AgroResearch Consortium (Beijing)
- Application: Herbicide lead optimization
- Result: 40% efficacy improvement
- Scale: 50kg pilot batch success
6. Contact for Custom Solutions
Technical Support Team:
Email: info@vivalr.com
Tel: (86) 15866781826
Request bulk pricing or discuss modified derivatives.


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