2-Methoxy-5-nitropyridine

Product Name:2-Methoxy-5-nitropyridine
CAS:5446-92-4
MFC6H6N2O3
MW:154.12
EINECS:226-661-7
MOL File:5446-92-4.mol

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2-Methoxy-5-nitropyridine: Technical Guide & Applications

1. Product Overview & Specifications

Parameter 2-Methoxy-5-nitropyridine Comparable Compounds
CAS Number 5446-92-4 127356-38-1 (4-amino variant)
Molecular Formula C6H6N2O3 C7H7NO4 (phenolic analog)
Appearance Off-white crystalline powder Varies by derivative
Storage 2-8°C, dry, inert atmosphere Similar requirements
Key Differentiator Pyridine core structure Benzene/phenol derivatives

2. Key Applications

This specialty chemical serves critical roles in:

  • Pharmaceutical intermediates for API synthesis
  • Agrochemical research & development
  • Ligand design in coordination chemistry
  • Building block for nitroaromatic compounds
  • Functional material development

3. Usage Guidelines

Handling Protocols

  • Use PPE: nitrile gloves, safety goggles
  • Process under nitrogen atmosphere
  • Limit exposure to moisture

Reaction Compatibility

  • Stable in polar aprotic solvents (DMF, DMSO)
  • Reactive toward nucleophilic substitution
  • Catalytic hydrogenation requires controlled conditions

4. Case Studies

Antimicrobial Agent Development

Used as key precursor in novel quinolone antibiotics synthesis, achieving 92% intermediate yield.

Electronic Materials

Enabled creation of nitro-functionalized conductive polymers with enhanced electron mobility.

5. Client Success Stories

Pharma Innovators Ltd. (Shanghai)

  • Application: Anticancer drug intermediate
  • Outcome: Reduced synthesis steps from 7 to 4
  • Purity Achieved: 99.7% (HPLC)

AgroResearch Consortium (Beijing)

  • Application: Herbicide lead optimization
  • Result: 40% efficacy improvement
  • Scale: 50kg pilot batch success

6. Contact for Custom Solutions

Technical Support Team:
Email: info@vivalr.com
Tel: (86) 15866781826

Request bulk pricing or discuss modified derivatives.

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