3,4-Lutidine: Technical Guide, Applications, and Case Studies
Table of Contents
1. Product Overview & Specifications
3,4-Lutidine (CAS 583-58-4) is a heterocyclic organic compound with the molecular formula C7H9N. This colorless to pale yellow liquid is widely used as a building block in pharmaceuticals, agrochemicals, and specialty chemicals.
Technical Parameters
| Parameter | 3,4-Lutidine | 2,4-Lutidine | 3,5-Lutidine |
|---|---|---|---|
| Purity | ≥99.5% | ≥98% | |
| Boiling Point | 162-164°C | 157-159°C | 171-173°C |
| Density (20°C) | 0.94 g/cm³ | 0.93 g/cm³ | 0.95 g/cm³ |
| Flash Point | 47°C | 45°C | 52°C |
2. Key Applications
Pharmaceutical Intermediates
Used in synthesis of antihypertensive drugs and neurological medications due to its excellent nucleophilic substitution reactivity.
Catalyst Systems
Serves as ligand in transition metal catalysts for asymmetric hydrogenation reactions (up to 95% enantiomeric excess).
Agrochemical Formulations
Critical component in next-generation fungicides and herbicides requiring pyridine derivatives.
3. Usage Scenarios
Pharmaceutical Production
In API synthesis: 3,4-Lutidine enables selective methylation at the 4-position under mild conditions (40-60°C, atmospheric pressure).
Electrolyte Additives
Improves lithium-ion battery cycle life by 18-22% when used at 0.5-1.5% concentration in electrolyte solutions.
4. Client Case Studies
Case 1: Top 5 Pharma Company
Challenge: Needed to improve yield in antipsychotic drug intermediate synthesis
Solution: Implemented 3,4-Lutidine-based catalyst system
Result: 31% yield increase, 99.2% purity achieved
Case 2: Agrochemical Leader
Challenge: Develop broad-spectrum fungicide with lower toxicity
Solution: Used 3,4-Lutidine as key building block
Result: Commercialized product with 98% efficacy at half dosage
5. Request a Quote
Our technical team provides:
- Batch-specific COA
- Custom synthesis options
- Regulatory support (REACH, FDA DMF)
Contact our specialists:
Email: info@vivalr.com
Tel: (86) 15866781826


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