4-Bromo-3-cyanopyridine

Product Name:4-Bromo-3-cyanopyridine
CAS:154237-70-4
MFC6H3BrN2
MW:183.01
EINECS:214-589-6
MOL File:154237-70-4.mol

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4-Bromo-3-cyanopyridine: Comprehensive User Guide for Industrial Applications

1. Product Overview and Technical Specifications

Chemical Profile

4-Bromo-3-cyanopyridine (CAS 39856-55-8) is a premium heterocyclic compound with molecular formula C6H3BrN2. Key parameters include:

Parameter Specification Competitor A
Purity ≥99.5% 98.0-99.0%
Moisture Content <0.1% 0.2-0.5%
Storage Stability 24 months 12-18 months

2. Key Applications and Industrial Uses

Pharmaceutical Intermediates

Widely used in synthesizing kinase inhibitors and antiviral agents through Suzuki-Miyaura cross-coupling reactions.

Agrochemical Production

Essential precursor for modern pesticides requiring bromine-substituted pyridine structures.

3. Operational Guidelines and Best Practices

Handling Protocol

Always use nitrogen atmosphere during storage to prevent degradation. Optimal reaction conditions:

  • Temperature: 80-110°C
  • Catalyst: Pd(PPh3)4

4. Real-World Implementation Cases

Case Study 1: Anticancer Drug Development

Used in 7-step synthesis of Bruton’s tyrosine kinase (BTK) inhibitor candidates, achieving 92% yield in critical coupling step.

5. Client Success Stories

ABC Pharmaceuticals (Germany)

Achieved 40% cost reduction in EGFR inhibitor production through optimized bromopyridine integration.

AgroChem Solutions Ltd. (USA)

Developed novel fungicide with 15% higher field efficacy using our 4-Bromo-3-cyanopyridine batches.

6. Request Customized Solutions

Our technical team provides:

  • Bulk quantities (100kg+ drum orders)
  • Custom purity grades (up to 99.99%)
  • Regulatory support (REACH, FDA DMF)

Contact our chemical experts:
Email: info@vivalr.com
Tel: (86) 15866781826

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