2-Bromo-5-chloropyridine: Comprehensive User Guide
Table of Contents
1. Product Specifications & Comparison
| Parameter | 2-Bromo-5-chloropyridine | Common Alternatives |
|---|---|---|
| CAS Number | 40473-01-6 | N/A |
| Molecular Formula | C5H3BrClN | C5H3BrClN (isomers) |
| Molecular Weight | 192.44 g/mol | 192.44 g/mol (isomers) |
| Physical State | Light brown to yellow crystalline powder | Varies by isomer |
| Melting Point | 65–69°C | 59–61°C (e.g., 3-Bromo-2-chloropyridine) |
| Density | 1.736 g/cm3 | 1.6–1.8 g/cm3 (typical for pyridine derivatives) |
2. Applications
2-Bromo-5-chloropyridine is a halogenated pyridine derivative widely used in:
- Pharmaceutical Intermediates: Key building block for synthesizing active pharmaceutical ingredients (APIs) targeting neurological and oncological diseases.
- Agrochemicals: Precursor in herbicides and fungicides due to its stability under harsh conditions.
- Material Science: Used in organic electronics and coordination chemistry for ligand design.
- Research & Development: Critical for cross-coupling reactions (e.g., Suzuki-Miyaura) to create complex heterocyclic systems.
3. Usage Scenarios
Scenario 1: API Synthesis
Used in a palladium-catalyzed coupling reaction to produce a kinase inhibitor intermediate, achieving >95% yield under optimized conditions.
Scenario 2: Herbicide Formulation
Integrated into a pre-emergent herbicide formulation, demonstrating 98% weed suppression in field trials.
4. Customer Case Studies
Case Study 1: Shanghai Xinyu Biotechnology Co., Ltd.
Challenge: Required high-purity (>98%) 2-Bromo-5-chloropyridine for a novel antipsychotic drug synthesis.
Solution: Supplied 50 kg of material with HPLC-certified purity of 99.2%, enabling successful scale-up to Phase II clinical trials.
Case Study 2: European Agrochemical Innovator
Challenge: Needed a stable halogenated precursor for a next-generation fungicide.
Solution: Provided custom synthesis services to deliver 200 kg batches with consistent impurity profiles (<0.5%).
5. Contact Information
For technical specifications, bulk orders, or custom synthesis inquiries:
| info@vivalr.com | |
| Phone | (86) 15866781826 |
| Lead Time | 2–4 weeks (standard orders) 6–8 weeks (custom synthesis) |


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