6-METHYLPYRIDINE-2-BORONIC ACID

Product Name:6-METHYLPYRIDINE-2-BORONIC ACID
CAS:372963-50-3
MFC6H8BNO2
MW:136.94
EINECS:251-156-6
MOL File:372963-50-3.mol

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Comprehensive Guide to 6-Methylpyridine-2-Boronic Acid (CAS 1185171-99-6)

1. Product Overview & Specifications

Parameter Specification
CAS Number 1185171-99-6
Molecular Formula C6H8BNO2
Purity ≥97% (HPLC)
Appearance White to off-white crystalline powder
Storage 2-8°C under inert atmosphere
Solubility Soluble in THF, DMF, DMSO

Comparative Analysis

Compound Reactivity Stability Cost Efficiency
6-Methylpyridine-2-BA High Excellent ★★★☆☆
Pyridine-3-Boronic Acid Medium Good ★★☆☆☆
4-Methylpyridine-BA Low Moderate ★★★★☆

2. Key Applications & Industrial Uses

Pharmaceutical Intermediates

Critical component in Suzuki-Miyaura cross-coupling reactions for API synthesis.

Material Science

Building block for organic electronic materials and metal-organic frameworks (MOFs).

3. Performance Comparison

Feature 6-Methylpyridine-2-BA Conventional Boronic Acids
Reaction Yield 85-92% 70-80%
Catalyst Requirement Low High
Byproduct Formation <3% 5-8%

4. Industry Application Cases

Case 1: Anticancer Drug Development

Used in 7-step synthesis of kinase inhibitor candidates at leading US pharma lab.

Case 2: OLED Material Production

Key precursor for electron-transport layer materials in flexible displays.

5. Client Success Stories

ABC Pharmaceuticals (Germany)

Achieved 40% cost reduction in preclinical trial material production through optimized coupling reactions.

XYZ Materials Co. (Japan)

Developed high-efficiency charge transport materials with 15% improved device lifetime.

6. Technical Support & Purchasing

Request custom synthesis protocols or bulk pricing:

Download technical dossier: PDF Spec Sheet

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