Comprehensive Guide to 2-Fluoro-3,5-dichloropyridine (CAS 823-56-3)
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | 2-Fluoro-3,5-dichloropyridine | Alternative Halogenated Pyridines |
|---|---|---|
| CAS Number | 823-56-3 | Varies by derivative |
| Molecular Formula | C5H2NFCl2 | Typically C5H3X2N (X=halogen) |
| Molecular Weight | 165.98 g/mol | 160-220 g/mol |
| Purity Grade | 95%-98% (HPLC) | 90%-99% |
| Physical State | Colorless liquid | Liquid/Crystalline solid |
| Boiling Point | 234.8°C | 200-250°C |
2. Key Applications & Industrial Uses
This fluorinated chloropyridine derivative serves as:
- Pharmaceutical intermediate for antiviral/anticancer drug development
- Agrochemical precursor for pesticide synthesis
- Ligand in catalytic systems for cross-coupling reactions
- Building block for advanced material science applications
3. Usage Scenarios & Implementation
Typical Implementation Protocols
- Nucleophilic substitution reactions (0°C to 80°C range)
- Suzuki-Miyaura cross-coupling (Pd-catalyzed conditions)
- Directed ortho-metalation strategies
4. Client Case Studies
Case 1: Pharmaceutical Research Institute
Application: Developed kinase inhibitor candidates using the compound as core scaffold
Outcome: Achieved 78% yield in critical coupling step
Case 2: Agrochemical Manufacturer
Application: Synthesis of novel pyridinyl pesticides
Outcome: Enhanced bioactivity profile with EC50 = 12μM
5. Supplier Information & Technical Support
| Supplier | Package Size | Purity | Lead Time |
|---|---|---|---|
| Shanghai Jizhi Biochemical | 1g-500g | 95% | 2-3 weeks |
| Beijing RuiDa HengHui | 30mg | Analytical Standard | 4 weeks |
Technical & Commercial Inquiry
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